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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T2153 | 1-NM-PP1 | PP1 Analog II,1 nM-PP1 | Serine/threonin kinase , CDK , Src |
1-NM-PP1 (PP1 Analog II) is a cell-permeable PP1 analog that acts as a potent and selective inhibitor of mutant kinases over their wild-type progenitors. | |||
T74359 | PP-C8 | ||
PP-C8, a potent and selective PROTAC CDK12-Cyclin K degrader, efficiently induces degradation of CDK12 and Cyclin K, with DC50 values of 416 nM and 412 nM, respectively. This compound exhibits significant synergistic ant... | |||
T79878 | Hydroxy-PP-Me | Apoptosis | |
Hydroxy-PP-Me is a potent and specific CBR1 inhibitor, exhibiting an IC50 of 759 nM. It not only inhibits serum-withdrawal-induced apoptosis but also enhances As2O3-induced apoptotic cell death when used in conjunction w... | |||
T36864 | GRP (human) (trifluoroacetate salt) | ||
Gastrin-releasing peptide (GRP) is a neuropeptide that stimulates gastrin release. It binds to (Ki = 300 nM) and stimulates amylase secretion in rat pancreatic AR42J cells (EC50 = 0.3 nM). GRP increases proliferation of ... |