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Vascular Endothelial Growth Factor Receptors, VEGFRs

Vascular Endothelial Growth Factor Receptors (VEGFRs) are receptors for vascular endothelial growth factor (VEGF). There are three main subtypes of VEGFR, numbered 1, 2 and 3. Depending on alternative splicing, they may be membrane-bound (mbVEGFR) or soluble (sVEGFR).The VEGF receptors have an extracellular portion consisting of 7 immunoglobulin-like domains, a single transmembrane spanning region and an intracellular portion containing a split tyrosine-kinase domain. VEGFR-2 appears to mediate almost all of the known cellular responses to VEGF. The function of VEGFR-1 is less well defined, although it is thought to modulate VEGFR-2 signaling. Another function of VEGFR-1 is to act as a dummy/decoy receptor, sequestering VEGF from VEGFR-2 binding. In fact, an alternatively spliced form of VEGFR-1 (sFlt1) is not a membrane bound protein but is secreted and functions primarily as a decoy. VEGFR-3 mediates lymphangiogenesis in response to VEGF-C and VEGF-D. Inhibitors of VEGFR are used in the treatment of cancer.

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Species
Cynomolgus (1)
Human (25)
Mouse (7)
Rat (3)
Rhesus (1)
Expression System
Baculovirus Insect Cells (1)
HEK293 Cells (36)
Tag
Avi (1)
C-6xHis (1)
C-6xHis-Avi (1)
C-Avi-His (1)
C-His (15)
C-His-Avi (7)
C-hFc (10)
GST (1)
His (2)
Cat No. product name / Synonyms Species Expression System
TMPY-04795 VEGFR2/KDR Protein, Human, Recombinant (Domain 1&2&3, His)
VEGFR2/KDR Protein, Human, Recombinant (Domain 1&2&3, His)
Human HEK293 Cells
VEGFR2/KDR Protein, Human, Recombinant (Domain 1&2&3, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 35.9 kDa and th...
TMPY-04796 VEGFR2/KDR Protein, Human, Recombinant (Domain 2&3, His)
VEGFR2/KDR Protein, Human, Recombinant (Domain 2&3, His)
Human HEK293 Cells
VEGFR2/KDR Protein, Human, Recombinant (Domain 2&3, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 24.8 kDa and the ...
TMPY-04802 VEGFR2/KDR Protein, Human, Recombinant (Domain 2&3, hFc)
VEGFR2/KDR Protein, Human, Recombinant (Domain 2&3, hFc)
Human HEK293 Cells
VEGFR2/KDR Protein, Human, Recombinant (Domain 2&3, hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 50.4 kDa and the ...
TMPY-04924 VEGFR2/KDR Protein, Mouse, Recombinant (His), Biotinylated
VEGFR2/KDR Protein, Mouse, Recombinant (His), Biotinylated
Mouse HEK293 Cells
VEGFR2/KDR Protein, Mouse, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 84.5 kDa and th...
TMPY-04940 VEGFR2/KDR Protein, Human, Recombinant (His), Biotinylated
VEGFR2/KDR Protein, Human, Recombinant (His), Biotinylated
Human HEK293 Cells
VEGFR2/KDR Protein, Human, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 84.6 kDa and th...
TMPY-05382 VEGFR2/KDR Protein, Cynomolgus, Recombinant (His)
VEGFR2/KDR Protein, Cynomolgus, Recombinant (His)
Cynomolgus HEK293 Cells
VEGFR2/KDR Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 84.7 kDa and the accessi...
TMPY-05610 VEGFR2/KDR Protein, Human, Recombinant (His & Avi), Biotinylated
VEGFR2/KDR Protein, Human, Recombinant (His & Avi), Biotinylated
Human HEK293 Cells
VEGFR2/KDR Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 8...
TMPY-05657 VEGFR2/KDR Protein, Human, Recombinant (hFc), Biotinylated
VEGFR2/KDR Protein, Human, Recombinant (hFc), Biotinylated
Human HEK293 Cells
VEGFR2/KDR Protein, Human, Recombinant (hFc), Biotinylated is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 61.5 kDa and th...
TMPY-05733 FLT1 Protein, Mouse, Recombinant (His)
FLT1 Protein, Mouse, Recombinant (His)
Mouse HEK293 Cells
FLT1 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 84.2 kDa and the accession number i...
TMPY-06620 VEGFR3/FLT4 Protein, Human, Recombinant (His & Avi), Biotinylated
VEGFR3/FLT4 Protein, Human, Recombinant (His & Avi), Biotinylated
Human HEK293 Cells
VEGFR3/FLT4 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is ...
TMPY-06665 FLT1 Protein, Mouse, Recombinant (His & Avi), Biotinylated
FLT1 Protein, Mouse, Recombinant (His & Avi), Biotinylated
Mouse HEK293 Cells
FLT1 Protein, Mouse, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 88.34 k...
TMPY-06780 FLT1 Protein, Human, Recombinant (His & Avi), Biotinylated
FLT1 Protein, Human, Recombinant (His & Avi), Biotinylated
Human HEK293 Cells
FLT1 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 85.45 k...
TMPY-01936 VEGFR3/FLT4 Protein, Mouse, Recombinant (His)
VEGFR3/FLT4 Protein, Mouse, Recombinant (His)
Mouse HEK293 Cells
VEGFR3/FLT4 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 86.4 kDa and the accession n...
TMPY-00637 FLT1 Protein, Human, Recombinant (aa 1-328, His)
FLT1 Protein, Human, Recombinant (aa 1-328, His)
Human HEK293 Cells
FLT1 Protein, Human, Recombinant (aa 1-328, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 35.6 kDa and the accessio...
TMPY-00949 VEGFR3/FLT4 Protein, Human, Recombinant (His)
VEGFR3/FLT4 Protein, Human, Recombinant (His)
Human HEK293 Cells
VEGFR3/FLT4 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 86 kDa and the accession num...
TMPY-02361 VEGFR2/KDR Protein, Human, Recombinant (His)
VEGFR2/KDR Protein, Human, Recombinant (His)
Human HEK293 Cells
VEGFR2/KDR Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 84.6 kDa and the accession nu...
TMPJ-00412 VEGFR1/FLT-1 Protein, Human, Recombinant (hFc)
VEGFR1/FLT-1 Protein, Human, Recombinant (hFc)
Human HEK293 Cells
Human Vascular endothelial growth factor receptor 1(VEGFR-1, FLT-1) is a member of the the class III subfamily of receptor tyrosine kinases (RTKs) and Tyr protei...
VEGFR2/KDR Protein, Human, Recombinant (Domain 1&2&3, His)
TMPY-04795
VEGFR2/KDR Protein, Human, Recombinant (Domain 1&2&3, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 35.9 kDa and th...
VEGFR2/KDR Protein, Human, Recombinant (Domain 2&3, His)
TMPY-04796
VEGFR2/KDR Protein, Human, Recombinant (Domain 2&3, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 24.8 kDa and the ...
VEGFR2/KDR Protein, Human, Recombinant (Domain 2&3, hFc)
TMPY-04802
VEGFR2/KDR Protein, Human, Recombinant (Domain 2&3, hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 50.4 kDa and the ...
VEGFR2/KDR Protein, Mouse, Recombinant (His), Biotinylated
TMPY-04924
VEGFR2/KDR Protein, Mouse, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 84.5 kDa and th...
VEGFR2/KDR Protein, Human, Recombinant (His), Biotinylated
TMPY-04940
VEGFR2/KDR Protein, Human, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 84.6 kDa and th...
VEGFR2/KDR Protein, Cynomolgus, Recombinant (His)
TMPY-05382
VEGFR2/KDR Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 84.7 kDa and the accessi...
VEGFR2/KDR Protein, Human, Recombinant (His & Avi), Biotinylated
TMPY-05610
VEGFR2/KDR Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 8...
VEGFR2/KDR Protein, Human, Recombinant (hFc), Biotinylated
TMPY-05657
VEGFR2/KDR Protein, Human, Recombinant (hFc), Biotinylated is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 61.5 kDa and th...
FLT1 Protein, Mouse, Recombinant (His)
TMPY-05733
FLT1 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 84.2 kDa and the accession number i...
VEGFR3/FLT4 Protein, Human, Recombinant (His & Avi), Biotinylated
TMPY-06620
VEGFR3/FLT4 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is ...
FLT1 Protein, Mouse, Recombinant (His & Avi), Biotinylated
TMPY-06665
FLT1 Protein, Mouse, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 88.34 k...
FLT1 Protein, Human, Recombinant (His & Avi), Biotinylated
TMPY-06780
FLT1 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 85.45 k...
VEGFR3/FLT4 Protein, Mouse, Recombinant (His)
TMPY-01936
VEGFR3/FLT4 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 86.4 kDa and the accession n...
FLT1 Protein, Human, Recombinant (aa 1-328, His)
TMPY-00637
FLT1 Protein, Human, Recombinant (aa 1-328, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 35.6 kDa and the accessio...
VEGFR3/FLT4 Protein, Human, Recombinant (His)
TMPY-00949
VEGFR3/FLT4 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 86 kDa and the accession num...
VEGFR2/KDR Protein, Human, Recombinant (His)
TMPY-02361
VEGFR2/KDR Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 84.6 kDa and the accession nu...
VEGFR1/FLT-1 Protein, Human, Recombinant (hFc)
TMPJ-00412
Human Vascular endothelial growth factor receptor 1(VEGFR-1, FLT-1) is a member of the the class III subfamily of receptor tyrosine kinases (RTKs) and Tyr protei...
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TargetMol