Epidermal growth factor (EGF) is a protein that stimulates cell growth and differentiation by binding to its receptor, EGFR. EGF acts by binding with high affinity to epidermal growth factor receptor (EGFR) on the cell surface. This stimulates ligand-induced dimerization, activating the intrinsic protein-tyrosine kinase activity of the receptor. The tyrosine kinase activity, in turn, initiates a signal transduction cascade that results in a variety of biochemical changes within the cell – a rise in intracellular calcium levels, increased glycolysis and protein synthesis, and increases in the expression of certain genes including the gene for EGFR – that ultimately lead to DNA synthesis and cell proliferation.
Cat No. | product name / Synonyms | Species | Expression System |
---|---|---|---|
TMPY-05062 | NRG2 Protein, Human, Recombinant (His)
NRG2 Protein, Human, Recombinant (His)
|
Human | HEK293 Cells |
Neuregulin-2 (NRG2) is a novel member of the neuregulin family of growth and differentiation factors. Through interaction with the ErbB family of receptors, neur... | |||
TMPY-05813 | Neuregulin-1/NRG1 Protein, Human, Recombinant , Biotinylated
Neuregulin-1/NRG1 Protein, Human, Recombinant , Biotinylated
|
Human | HEK293 Cells |
Neuregulin-1/NRG1 Protein, Human, Recombinant , Biotinylated is expressed in HEK293 mammalian cells. The predicted molecular weight is 26.8 kDa and the accession... | |||
TMPY-06493 | EGF Protein, Feline, Recombinant (hFc)
EGF Protein, Feline, Recombinant (hFc)
|
Feline | HEK293 Cells |
EGF Protein, Feline, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 34.63 kDa and the accession number ... | |||
TMPY-06597 | Betacellulin Protein, Rhesus, Recombinant (hFc)
Betacellulin Protein, Rhesus, Recombinant (hFc)
|
Rhesus | HEK293 Cells |
Betacellulin Protein, Rhesus, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 36 kDa and the accession n... | |||
TMPY-06984 | EGF Protein, Mouse, Recombinant (Yeast)
EGF Protein, Mouse, Recombinant (Yeast)
|
Mouse | P. pastoris (Yeast) |
EGF Protein, Mouse, Recombinant (Yeast) is expressed in yeast. The predicted molecular weight is 6 KDa. and the accession number is P01132. | |||
TMPY-06984 | EGF Protein, Mouse, Recombinant (Yeast)
EGF Protein, Mouse, Recombinant (Yeast)
|
Mouse | P. pastoris (Yeast) |
EGF Protein, Mouse, Recombinant (Yeast) is expressed in yeast. The predicted molecular weight is 6 KDa. and the accession number is P01132. | |||
TMPY-06984 | EGF Protein, Mouse, Recombinant (Yeast)
EGF Protein, Mouse, Recombinant (Yeast)
|
Mouse | P. pastoris (Yeast) |
EGF Protein, Mouse, Recombinant (Yeast) is expressed in yeast. The predicted molecular weight is 6 KDa. and the accession number is P01132. | |||
TMPY-06984 | EGF Protein, Mouse, Recombinant (Yeast)
EGF Protein, Mouse, Recombinant (Yeast)
|
Mouse | P. pastoris (Yeast) |
EGF Protein, Mouse, Recombinant (Yeast) is expressed in yeast. The predicted molecular weight is 6 KDa. and the accession number is P01132. | |||
TMPY-01062 | EGF Protein, Human, Recombinant (hFc)
EGF Protein, Human, Recombinant (hFc)
|
Human | HEK293 Cells |
EGF Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 33 kDa and the accession number is P... | |||
TMPY-01560 | EGF Protein, Human, Recombinant
EGF Protein, Human, Recombinant
|
Human | E. coli |
EGF Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 6.35 kDa and the accession number is P01133-1. | |||
TMPY-03958 | TGF alpha Protein, Human, Recombinant
TGF alpha Protein, Human, Recombinant
|
Human | E. coli |
The miR-137 served as a tumor suppressor in non-small cell lung cancer (NSCLC) and its suppressive effect is mediated by repressing TGFA expression. TGFA gene ex... |