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Epidermal Growth Factor Family, EGFs

Epidermal growth factor (EGF) is a protein that stimulates cell growth and differentiation by binding to its receptor, EGFR. EGF acts by binding with high affinity to epidermal growth factor receptor (EGFR) on the cell surface. This stimulates ligand-induced dimerization, activating the intrinsic protein-tyrosine kinase activity of the receptor. The tyrosine kinase activity, in turn, initiates a signal transduction cascade that results in a variety of biochemical changes within the cell – a rise in intracellular calcium levels, increased glycolysis and protein synthesis, and increases in the expression of certain genes including the gene for EGFR – that ultimately lead to DNA synthesis and cell proliferation.

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Species
Canine (7)
Feline (1)
Human (26)
Mouse (15)
Rat (1)
Rhesus (1)
Expression System
Baculovirus Insect Cells (4)
E. coli (8)
HEK293 Cells (34)
P. pastoris (Yeast) (5)
Tag
C-His (8)
C-His & N-Flag (1)
C-hFc (7)
C-hFc-His (1)
N-6xHis (1)
N-His (4)
N-hFc (13)
N-mFc (1)
Tag Free (15)
Cat No. product name / Synonyms Species Expression System
TMPJ-00058 BTC Protein, Mouse, Recombinant (His)
BTC Protein, Mouse, Recombinant (His)
Mouse E. coli
Mouse Betacellulin is a single type I membrane protein which belongs to the EGF family of cytokines. EGF family has many members including EGF, TGF-a, Amphiregul...
TMPJ-00448 NRG1 beta 1 Protein, Human, Recombinant (aa 2-246)
NRG1 beta 1 Protein, Human, Recombinant (aa 2-246)
Human E. coli
Pro-neuregulin-1,Neuregulin-1 beta 1(NRG1) is a single-pass type I membrane protein and belongs to the neuregulin family .It contains 1 EGF-like domain and 1 Ig...
TMPJ-00859 AREG Protein, Human, Recombinant
AREG Protein, Human, Recombinant
Human E. coli
Amphiregulin (AREG) is a single-pass membrane protein with 252 amino acids. AREG belongs to the amphiregulin family, which contains 1 EGF-like domain. AREG is ex...
TMPK-00757 TGF alpha Protein, Human, Recombinant (hFc)
TGF alpha Protein, Human, Recombinant (hFc)
Human HEK293 Cells
Transforming growth factor-alpha (TGFA) has been proposed as a candidate gene in the etiology of nonsyndromic cleft lip with or without cleft palate (NS-CL/P) an...
TMPK-00820 AREG Protein, Human, Recombinant (hFc)
AREG Protein, Human, Recombinant (hFc)
Human HEK293 Cells
Amphiregulin (AREG) is a member of the epidermal growth factor (EGF) family and is expressed in a plethora of cancers. Tumour growth and metastasis were decrease...
TMPK-00870 AREG Protein, Mouse, Recombinant (hFc)
AREG Protein, Mouse, Recombinant (hFc)
Mouse HEK293 Cells
Amphiregulin (AREG) is a ligand of the epidermal growth factor receptor (EGFR), a widely expressed transmembrane tyrosine kinase. AREG is synthesized as a membra...
TMPK-00888 TGF alpha Protein, Mouse, Recombinant (hFc)
TGF alpha Protein, Mouse, Recombinant (hFc)
Mouse HEK293 Cells
Transforming growth factor-alpha (TGFA) has been proposed as a candidate gene in the etiology of nonsyndromic cleft lip with or without cleft palate (NS-CL/P) an...
TMPY-00031 Neuregulin-1/NRG1 Protein, Human, Recombinant (His)
Neuregulin-1/NRG1 Protein, Human, Recombinant (His)
Human HEK293 Cells
Neuregulin-1/NRG1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 25.3 kDa and the acces...
TMPY-00078 EGFL6 Protein, Mouse, Recombinant (His)
EGFL6 Protein, Mouse, Recombinant (His)
Mouse HEK293 Cells
EGFL6 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 31.5 kDa and the accession number ...
TMPY-00094 EGFL6 Protein, Mouse, Recombinant (hFc)
EGFL6 Protein, Mouse, Recombinant (hFc)
Mouse HEK293 Cells
EGFL6 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 56.8 kDa and the accession number ...
TMPY-00192 NRG3 Protein, Human, Recombinant (hFc)
NRG3 Protein, Human, Recombinant (hFc)
Human HEK293 Cells
NRG3 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 33.7 kDa and the accession number i...
TMPY-00220 EGF Protein, Mouse, Recombinant (His)
EGF Protein, Mouse, Recombinant (His)
Mouse HEK293 Cells
EGF Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 111.3 kDa and the accession number i...
TMPY-00343 RTN4RL1 Protein, Human, Recombinant (hFc)
RTN4RL1 Protein, Human, Recombinant (hFc)
Human HEK293 Cells
RTN4RL1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 71.5 kDa and the accession numbe...
TMPY-00479 Neuregulin-1/NRG1 Protein, Human, Recombinant (hFc)
Neuregulin-1/NRG1 Protein, Human, Recombinant (hFc)
Human HEK293 Cells
Neuregulin-1/NRG1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 35.5 kDa and the acces...
TMPY-01323 Betacellulin Protein, Mouse, Recombinant (His & hFc)
Betacellulin Protein, Mouse, Recombinant (His & hFc)
Mouse HEK293 Cells
Betacellulin Protein, Mouse, Recombinant (His & hFc) is expressed in HEK293 mammalian cells with His and hFc tag. The predicted molecular weight is 38 kDa and th...
TMPY-02166 Epiregulin Protein, Mouse, Recombinant (hFc)
Epiregulin Protein, Mouse, Recombinant (hFc)
Mouse HEK293 Cells
Epiregulin Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 33.8 kDa and the accession nu...
TMPY-02169 Epiregulin Protein, Human, Recombinant (hFc)
Epiregulin Protein, Human, Recombinant (hFc)
Human HEK293 Cells
Epiregulin Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 33.8 kDa and the accession nu...
TMPY-02178 EGFL7 Protein, Mouse, Recombinant (His)
EGFL7 Protein, Mouse, Recombinant (His)
Mouse Baculovirus Insect Cells
EGFL7 Protein, Mouse, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 29.8 kDa and the accession numbe...
TMPY-02267 EGF Protein, Mouse, Recombinant (hFc)
EGF Protein, Mouse, Recombinant (hFc)
Mouse HEK293 Cells
EGF Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 34.5 kDa and the accession number is...
TMPY-02539 EGF Protein, Canine, Recombinant (His)
EGF Protein, Canine, Recombinant (His)
Canine E. coli
EGF Protein, Canine, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 8.3 kDa and the accession number...
BTC Protein, Mouse, Recombinant (His)
TMPJ-00058
Mouse Betacellulin is a single type I membrane protein which belongs to the EGF family of cytokines. EGF family has many members including EGF, TGF-a, Amphiregul...
NRG1 beta 1 Protein, Human, Recombinant (aa 2-246)
TMPJ-00448
Pro-neuregulin-1,Neuregulin-1 beta 1(NRG1) is a single-pass type I membrane protein and belongs to the neuregulin family .It contains 1 EGF-like domain and 1 Ig...
AREG Protein, Human, Recombinant
TMPJ-00859
Amphiregulin (AREG) is a single-pass membrane protein with 252 amino acids. AREG belongs to the amphiregulin family, which contains 1 EGF-like domain. AREG is ex...
TGF alpha Protein, Human, Recombinant (hFc)
TMPK-00757
Transforming growth factor-alpha (TGFA) has been proposed as a candidate gene in the etiology of nonsyndromic cleft lip with or without cleft palate (NS-CL/P) an...
AREG Protein, Human, Recombinant (hFc)
TMPK-00820
Amphiregulin (AREG) is a member of the epidermal growth factor (EGF) family and is expressed in a plethora of cancers. Tumour growth and metastasis were decrease...
AREG Protein, Mouse, Recombinant (hFc)
TMPK-00870
Amphiregulin (AREG) is a ligand of the epidermal growth factor receptor (EGFR), a widely expressed transmembrane tyrosine kinase. AREG is synthesized as a membra...
TGF alpha Protein, Mouse, Recombinant (hFc)
TMPK-00888
Transforming growth factor-alpha (TGFA) has been proposed as a candidate gene in the etiology of nonsyndromic cleft lip with or without cleft palate (NS-CL/P) an...
Neuregulin-1/NRG1 Protein, Human, Recombinant (His)
TMPY-00031
Neuregulin-1/NRG1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 25.3 kDa and the acces...
EGFL6 Protein, Mouse, Recombinant (His)
TMPY-00078
EGFL6 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 31.5 kDa and the accession number ...
EGFL6 Protein, Mouse, Recombinant (hFc)
TMPY-00094
EGFL6 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 56.8 kDa and the accession number ...
NRG3 Protein, Human, Recombinant (hFc)
TMPY-00192
NRG3 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 33.7 kDa and the accession number i...
EGF Protein, Mouse, Recombinant (His)
TMPY-00220
EGF Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 111.3 kDa and the accession number i...
RTN4RL1 Protein, Human, Recombinant (hFc)
TMPY-00343
RTN4RL1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 71.5 kDa and the accession numbe...
Neuregulin-1/NRG1 Protein, Human, Recombinant (hFc)
TMPY-00479
Neuregulin-1/NRG1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 35.5 kDa and the acces...
Betacellulin Protein, Mouse, Recombinant (His & hFc)
TMPY-01323
Betacellulin Protein, Mouse, Recombinant (His & hFc) is expressed in HEK293 mammalian cells with His and hFc tag. The predicted molecular weight is 38 kDa and th...
Epiregulin Protein, Mouse, Recombinant (hFc)
TMPY-02166
Epiregulin Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 33.8 kDa and the accession nu...
Epiregulin Protein, Human, Recombinant (hFc)
TMPY-02169
Epiregulin Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 33.8 kDa and the accession nu...
EGFL7 Protein, Mouse, Recombinant (His)
TMPY-02178
EGFL7 Protein, Mouse, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 29.8 kDa and the accession numbe...
EGF Protein, Mouse, Recombinant (hFc)
TMPY-02267
EGF Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 34.5 kDa and the accession number is...
EGF Protein, Canine, Recombinant (His)
TMPY-02539
EGF Protein, Canine, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 8.3 kDa and the accession number...
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TargetMol