Epidermal growth factor (EGF) is a protein that stimulates cell growth and differentiation by binding to its receptor, EGFR. EGF acts by binding with high affinity to epidermal growth factor receptor (EGFR) on the cell surface. This stimulates ligand-induced dimerization, activating the intrinsic protein-tyrosine kinase activity of the receptor. The tyrosine kinase activity, in turn, initiates a signal transduction cascade that results in a variety of biochemical changes within the cell – a rise in intracellular calcium levels, increased glycolysis and protein synthesis, and increases in the expression of certain genes including the gene for EGFR – that ultimately lead to DNA synthesis and cell proliferation.
Cat No. | product name / Synonyms | Species | Expression System |
---|---|---|---|
TMPJ-00058 | BTC Protein, Mouse, Recombinant (His)
BTC Protein, Mouse, Recombinant (His)
|
Mouse | E. coli |
Mouse Betacellulin is a single type I membrane protein which belongs to the EGF family of cytokines. EGF family has many members including EGF, TGF-a, Amphiregul... | |||
TMPJ-00448 | NRG1 beta 1 Protein, Human, Recombinant (aa 2-246)
NRG1 beta 1 Protein, Human, Recombinant (aa 2-246)
|
Human | E. coli |
Pro-neuregulin-1,Neuregulin-1 beta 1(NRG1) is a single-pass type I membrane protein and belongs to the neuregulin family .It contains 1 EGF-like domain and 1 Ig... | |||
TMPJ-00859 | AREG Protein, Human, Recombinant
AREG Protein, Human, Recombinant
|
Human | E. coli |
Amphiregulin (AREG) is a single-pass membrane protein with 252 amino acids. AREG belongs to the amphiregulin family, which contains 1 EGF-like domain. AREG is ex... | |||
TMPK-00757 | TGF alpha Protein, Human, Recombinant (hFc)
TGF alpha Protein, Human, Recombinant (hFc)
|
Human | HEK293 Cells |
Transforming growth factor-alpha (TGFA) has been proposed as a candidate gene in the etiology of nonsyndromic cleft lip with or without cleft palate (NS-CL/P) an... | |||
TMPK-00820 | AREG Protein, Human, Recombinant (hFc)
AREG Protein, Human, Recombinant (hFc)
|
Human | HEK293 Cells |
Amphiregulin (AREG) is a member of the epidermal growth factor (EGF) family and is expressed in a plethora of cancers. Tumour growth and metastasis were decrease... | |||
TMPK-00870 | AREG Protein, Mouse, Recombinant (hFc)
AREG Protein, Mouse, Recombinant (hFc)
|
Mouse | HEK293 Cells |
Amphiregulin (AREG) is a ligand of the epidermal growth factor receptor (EGFR), a widely expressed transmembrane tyrosine kinase. AREG is synthesized as a membra... | |||
TMPK-00888 | TGF alpha Protein, Mouse, Recombinant (hFc)
TGF alpha Protein, Mouse, Recombinant (hFc)
|
Mouse | HEK293 Cells |
Transforming growth factor-alpha (TGFA) has been proposed as a candidate gene in the etiology of nonsyndromic cleft lip with or without cleft palate (NS-CL/P) an... | |||
TMPY-00031 | Neuregulin-1/NRG1 Protein, Human, Recombinant (His)
Neuregulin-1/NRG1 Protein, Human, Recombinant (His)
|
Human | HEK293 Cells |
Neuregulin-1/NRG1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 25.3 kDa and the acces... | |||
TMPY-00078 | EGFL6 Protein, Mouse, Recombinant (His)
EGFL6 Protein, Mouse, Recombinant (His)
|
Mouse | HEK293 Cells |
EGFL6 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 31.5 kDa and the accession number ... | |||
TMPY-00094 | EGFL6 Protein, Mouse, Recombinant (hFc)
EGFL6 Protein, Mouse, Recombinant (hFc)
|
Mouse | HEK293 Cells |
EGFL6 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 56.8 kDa and the accession number ... | |||
TMPY-00192 | NRG3 Protein, Human, Recombinant (hFc)
NRG3 Protein, Human, Recombinant (hFc)
|
Human | HEK293 Cells |
NRG3 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 33.7 kDa and the accession number i... | |||
TMPY-00220 | EGF Protein, Mouse, Recombinant (His)
EGF Protein, Mouse, Recombinant (His)
|
Mouse | HEK293 Cells |
EGF Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 111.3 kDa and the accession number i... | |||
TMPY-00343 | RTN4RL1 Protein, Human, Recombinant (hFc)
RTN4RL1 Protein, Human, Recombinant (hFc)
|
Human | HEK293 Cells |
RTN4RL1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 71.5 kDa and the accession numbe... | |||
TMPY-00479 | Neuregulin-1/NRG1 Protein, Human, Recombinant (hFc)
Neuregulin-1/NRG1 Protein, Human, Recombinant (hFc)
|
Human | HEK293 Cells |
Neuregulin-1/NRG1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 35.5 kDa and the acces... | |||
TMPY-01323 | Betacellulin Protein, Mouse, Recombinant (His & hFc)
Betacellulin Protein, Mouse, Recombinant (His & hFc)
|
Mouse | HEK293 Cells |
Betacellulin Protein, Mouse, Recombinant (His & hFc) is expressed in HEK293 mammalian cells with His and hFc tag. The predicted molecular weight is 38 kDa and th... | |||
TMPY-02166 | Epiregulin Protein, Mouse, Recombinant (hFc)
Epiregulin Protein, Mouse, Recombinant (hFc)
|
Mouse | HEK293 Cells |
Epiregulin Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 33.8 kDa and the accession nu... | |||
TMPY-02169 | Epiregulin Protein, Human, Recombinant (hFc)
Epiregulin Protein, Human, Recombinant (hFc)
|
Human | HEK293 Cells |
Epiregulin Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 33.8 kDa and the accession nu... | |||
TMPY-02178 | EGFL7 Protein, Mouse, Recombinant (His)
EGFL7 Protein, Mouse, Recombinant (His)
|
Mouse | Baculovirus Insect Cells |
EGFL7 Protein, Mouse, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 29.8 kDa and the accession numbe... | |||
TMPY-02267 | EGF Protein, Mouse, Recombinant (hFc)
EGF Protein, Mouse, Recombinant (hFc)
|
Mouse | HEK293 Cells |
EGF Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 34.5 kDa and the accession number is... | |||
TMPY-02539 | EGF Protein, Canine, Recombinant (His)
EGF Protein, Canine, Recombinant (His)
|
Canine | E. coli |
EGF Protein, Canine, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 8.3 kDa and the accession number... |