Epidermal growth factor (EGF) is a protein that stimulates cell growth and differentiation by binding to its receptor, EGFR. EGF acts by binding with high affinity to epidermal growth factor receptor (EGFR) on the cell surface. This stimulates ligand-induced dimerization, activating the intrinsic protein-tyrosine kinase activity of the receptor. The tyrosine kinase activity, in turn, initiates a signal transduction cascade that results in a variety of biochemical changes within the cell – a rise in intracellular calcium levels, increased glycolysis and protein synthesis, and increases in the expression of certain genes including the gene for EGFR – that ultimately lead to DNA synthesis and cell proliferation.
Cat No. | product name / Synonyms | Species | Expression System |
---|---|---|---|
TMPJ-00058 | BTC Protein, Mouse, Recombinant (His)
BTC Protein, Mouse, Recombinant (His)
|
Mouse | E. coli |
Mouse Betacellulin is a single type I membrane protein which belongs to the EGF family of cytokines. EGF family has many members including EGF, TGF-a, Amphiregul... | |||
TMPJ-00448 | NRG1 beta 1 Protein, Human, Recombinant (aa 2-246)
NRG1 beta 1 Protein, Human, Recombinant (aa 2-246)
|
Human | E. coli |
Pro-neuregulin-1,Neuregulin-1 beta 1(NRG1) is a single-pass type I membrane protein and belongs to the neuregulin family .It contains 1 EGF-like domain and 1 Ig... | |||
TMPJ-00859 | AREG Protein, Human, Recombinant
AREG Protein, Human, Recombinant
|
Human | E. coli |
Amphiregulin (AREG) is a single-pass membrane protein with 252 amino acids. AREG belongs to the amphiregulin family, which contains 1 EGF-like domain. AREG is ex... | |||
TMPK-00757 | TGF alpha Protein, Human, Recombinant (hFc)
TGF alpha Protein, Human, Recombinant (hFc)
|
Human | HEK293 |
Transforming growth factor-alpha (TGFA) has been proposed as a candidate gene in the etiology of nonsyndromic cleft lip with or without cleft palate (NS-CL/P) an... | |||
TMPK-00820 | AREG Protein, Human, Recombinant (hFc)
AREG Protein, Human, Recombinant (hFc)
|
Human | HEK293 |
Amphiregulin (AREG) is a member of the epidermal growth factor (EGF) family and is expressed in a plethora of cancers. Tumour growth and metastasis were decrease... | |||
TMPK-00870 | AREG Protein, Mouse, Recombinant (hFc)
AREG Protein, Mouse, Recombinant (hFc)
|
Mouse | HEK293 |
Amphiregulin (AREG) is a ligand of the epidermal growth factor receptor (EGFR), a widely expressed transmembrane tyrosine kinase. AREG is synthesized as a membra... | |||
TMPK-00888 | TGF alpha Protein, Mouse, Recombinant (hFc)
TGF alpha Protein, Mouse, Recombinant (hFc)
|
Mouse | HEK293 |
Transforming growth factor-alpha (TGFA) has been proposed as a candidate gene in the etiology of nonsyndromic cleft lip with or without cleft palate (NS-CL/P) an... | |||
TMPY-00031 | Neuregulin-1/NRG1 Protein, Human, Recombinant (His)
Neuregulin-1/NRG1 Protein, Human, Recombinant (His)
|
Human | HEK293 |
Neuregulin 1 or NRG1 is one of four proteins in the neuregulin family that act on the EGFR family of receptors. This growth factor was originally identified as a... | |||
TMPY-00078 | EGFL6 Protein, Mouse, Recombinant (His)
EGFL6 Protein, Mouse, Recombinant (His)
|
Mouse | HEK293 |
EGFL6, also known as EGF-L6, belongs to the epidermal growth factor (EGF) repeat superfamily. Members of this superfamily are characterized by the presence of EG... | |||
TMPY-00094 | EGFL6 Protein, Mouse, Recombinant (hFc)
EGFL6 Protein, Mouse, Recombinant (hFc)
|
Mouse | HEK293 |
EGFL6, also known as EGF-L6, belongs to the epidermal growth factor (EGF) repeat superfamily. Members of this superfamily are characterized by the presence of EG... | |||
TMPY-00192 | NRG3 Protein, Human, Recombinant (hFc)
NRG3 Protein, Human, Recombinant (hFc)
|
Human | HEK293 |
NRG3 (Neuregulin 3) is a Protein Coding gene. NRG3 is a member of the neuregulin family of EGF proteins. It has been shown to activate the tyrosine phosphorylati... | |||
TMPY-00220 | EGF Protein, Mouse, Recombinant (His)
EGF Protein, Mouse, Recombinant (His)
|
Mouse | HEK293 |
EGF is the founding member of the EGF-family of proteins. Members of this protein family have highly similar structural and functional characteristics. EGF conta... | |||
TMPY-00343 | RTN4RL1 Protein, Human, Recombinant (hFc)
RTN4RL1 Protein, Human, Recombinant (hFc)
|
Human | HEK293 |
RTN4RL1 Protein, Human, Recombinant (hFc) is expressed in HEK293 with hFc tag. The predicted molecular weight is 71.5 kDa. Accession number: Q86UN2 | |||
TMPY-00479 | Neuregulin-1/NRG1 Protein, Human, Recombinant (hFc)
Neuregulin-1/NRG1 Protein, Human, Recombinant (hFc)
|
Human | HEK293 |
Neuregulin 1 or NRG1 is one of four proteins in the neuregulin family that act on the EGFR family of receptors. This growth factor was originally identified as a... | |||
TMPY-01323 | Betacellulin Protein, Mouse, Recombinant (His & hFc)
Betacellulin Protein, Mouse, Recombinant (His & hFc)
|
Mouse | HEK293 |
Betacellulin(BTC) is a member of the epidermal growth factor (EGF) family. These soluble proteins are ligands for one or more of the four receptor tyrosine kinas... | |||
TMPY-02166 | Epiregulin Protein, Mouse, Recombinant (hFc)
Epiregulin Protein, Mouse, Recombinant (hFc)
|
Mouse | HEK293 |
Epiregulin (EREG) is a member of the epidermal growth factor family. Epiregulin (EREG) can function as a ligand of EGFR (epidermal growth factor receptor), as we... | |||
TMPY-02169 | Epiregulin Protein, Human, Recombinant (hFc)
Epiregulin Protein, Human, Recombinant (hFc)
|
Human | HEK293 |
Epiregulin (EREG) is a member of the epidermal growth factor family. Epiregulin (EREG) can function as a ligand of EGFR (epidermal growth factor receptor), as we... | |||
TMPY-02178 | EGFL7 Protein, Mouse, Recombinant (His)
EGFL7 Protein, Mouse, Recombinant (His)
|
Mouse | Baculovirus-Insect Cells |
Epidermal growth factor-like protein 7, also known as EGF-like protein 7, Multiple epidermal growth factor-like domains protein 7, Multiple EGF-like domains pr... | |||
TMPY-02267 | EGF Protein, Mouse, Recombinant (hFc)
EGF Protein, Mouse, Recombinant (hFc)
|
Mouse | HEK293 |
EGF is the founding member of the EGF-family of proteins. Members of this protein family have highly similar structural and functional characteristics. EGF conta... | |||
TMPY-02539 | EGF Protein, Canine, Recombinant (His)
EGF Protein, Canine, Recombinant (His)
|
Canine | E. coli |
EGF is the founding member of the EGF-family of proteins. Members of this protein family have highly similar structural and functional characteristics. EGF conta... |