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Epidermal Growth Factor Family, EGFs

Epidermal growth factor (EGF) is a protein that stimulates cell growth and differentiation by binding to its receptor, EGFR. EGF acts by binding with high affinity to epidermal growth factor receptor (EGFR) on the cell surface. This stimulates ligand-induced dimerization, activating the intrinsic protein-tyrosine kinase activity of the receptor. The tyrosine kinase activity, in turn, initiates a signal transduction cascade that results in a variety of biochemical changes within the cell – a rise in intracellular calcium levels, increased glycolysis and protein synthesis, and increases in the expression of certain genes including the gene for EGFR – that ultimately lead to DNA synthesis and cell proliferation.

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Species
Canine (7)
Feline (1)
Human (26)
Mouse (15)
Rat (1)
Rhesus (1)
Expression System
Baculovirus-Insect Cells (4)
E. coli (8)
HEK293 (34)
Yeast (5)
Tag
FLAG (1)
Fc (4)
His (14)
N-6His (1)
N-hFc (4)
None (2)
Tag Free (13)
hFc (13)
mFc (1)
Cat No. product name / Synonyms Species Expression System
TMPJ-00058 BTC Protein, Mouse, Recombinant (His)
BTC Protein, Mouse, Recombinant (His)
Mouse E. coli
Mouse Betacellulin is a single type I membrane protein which belongs to the EGF family of cytokines. EGF family has many members including EGF, TGF-a, Amphiregul...
TMPJ-00448 NRG1 beta 1 Protein, Human, Recombinant (aa 2-246)
NRG1 beta 1 Protein, Human, Recombinant (aa 2-246)
Human E. coli
Pro-neuregulin-1,Neuregulin-1 beta 1(NRG1) is a single-pass type I membrane protein and belongs to the neuregulin family .It contains 1 EGF-like domain and 1 Ig...
TMPJ-00859 AREG Protein, Human, Recombinant
AREG Protein, Human, Recombinant
Human E. coli
Amphiregulin (AREG) is a single-pass membrane protein with 252 amino acids. AREG belongs to the amphiregulin family, which contains 1 EGF-like domain. AREG is ex...
TMPK-00757 TGF alpha Protein, Human, Recombinant (hFc)
TGF alpha Protein, Human, Recombinant (hFc)
Human HEK293
Transforming growth factor-alpha (TGFA) has been proposed as a candidate gene in the etiology of nonsyndromic cleft lip with or without cleft palate (NS-CL/P) an...
TMPK-00820 AREG Protein, Human, Recombinant (hFc)
AREG Protein, Human, Recombinant (hFc)
Human HEK293
Amphiregulin (AREG) is a member of the epidermal growth factor (EGF) family and is expressed in a plethora of cancers. Tumour growth and metastasis were decrease...
TMPK-00870 AREG Protein, Mouse, Recombinant (hFc)
AREG Protein, Mouse, Recombinant (hFc)
Mouse HEK293
Amphiregulin (AREG) is a ligand of the epidermal growth factor receptor (EGFR), a widely expressed transmembrane tyrosine kinase. AREG is synthesized as a membra...
TMPK-00888 TGF alpha Protein, Mouse, Recombinant (hFc)
TGF alpha Protein, Mouse, Recombinant (hFc)
Mouse HEK293
Transforming growth factor-alpha (TGFA) has been proposed as a candidate gene in the etiology of nonsyndromic cleft lip with or without cleft palate (NS-CL/P) an...
TMPY-00031 Neuregulin-1/NRG1 Protein, Human, Recombinant (His)
Neuregulin-1/NRG1 Protein, Human, Recombinant (His)
Human HEK293
Neuregulin 1 or NRG1 is one of four proteins in the neuregulin family that act on the EGFR family of receptors. This growth factor was originally identified as a...
TMPY-00078 EGFL6 Protein, Mouse, Recombinant (His)
EGFL6 Protein, Mouse, Recombinant (His)
Mouse HEK293
EGFL6, also known as EGF-L6, belongs to the epidermal growth factor (EGF) repeat superfamily. Members of this superfamily are characterized by the presence of EG...
TMPY-00094 EGFL6 Protein, Mouse, Recombinant (hFc)
EGFL6 Protein, Mouse, Recombinant (hFc)
Mouse HEK293
EGFL6, also known as EGF-L6, belongs to the epidermal growth factor (EGF) repeat superfamily. Members of this superfamily are characterized by the presence of EG...
TMPY-00192 NRG3 Protein, Human, Recombinant (hFc)
NRG3 Protein, Human, Recombinant (hFc)
Human HEK293
NRG3 (Neuregulin 3) is a Protein Coding gene. NRG3 is a member of the neuregulin family of EGF proteins. It has been shown to activate the tyrosine phosphorylati...
TMPY-00220 EGF Protein, Mouse, Recombinant (His)
EGF Protein, Mouse, Recombinant (His)
Mouse HEK293
EGF is the founding member of the EGF-family of proteins. Members of this protein family have highly similar structural and functional characteristics. EGF conta...
TMPY-00343 RTN4RL1 Protein, Human, Recombinant (hFc)
RTN4RL1 Protein, Human, Recombinant (hFc)
Human HEK293
RTN4RL1 Protein, Human, Recombinant (hFc) is expressed in HEK293 with hFc tag. The predicted molecular weight is 71.5 kDa. Accession number: Q86UN2
TMPY-00479 Neuregulin-1/NRG1 Protein, Human, Recombinant (hFc)
Neuregulin-1/NRG1 Protein, Human, Recombinant (hFc)
Human HEK293
Neuregulin 1 or NRG1 is one of four proteins in the neuregulin family that act on the EGFR family of receptors. This growth factor was originally identified as a...
TMPY-01323 Betacellulin Protein, Mouse, Recombinant (His & hFc)
Betacellulin Protein, Mouse, Recombinant (His & hFc)
Mouse HEK293
Betacellulin(BTC) is a member of the epidermal growth factor (EGF) family. These soluble proteins are ligands for one or more of the four receptor tyrosine kinas...
TMPY-02166 Epiregulin Protein, Mouse, Recombinant (hFc)
Epiregulin Protein, Mouse, Recombinant (hFc)
Mouse HEK293
Epiregulin (EREG) is a member of the epidermal growth factor family. Epiregulin (EREG) can function as a ligand of EGFR (epidermal growth factor receptor), as we...
TMPY-02169 Epiregulin Protein, Human, Recombinant (hFc)
Epiregulin Protein, Human, Recombinant (hFc)
Human HEK293
Epiregulin (EREG) is a member of the epidermal growth factor family. Epiregulin (EREG) can function as a ligand of EGFR (epidermal growth factor receptor), as we...
TMPY-02178 EGFL7 Protein, Mouse, Recombinant (His)
EGFL7 Protein, Mouse, Recombinant (His)
Mouse Baculovirus-Insect Cells
Epidermal growth factor-like protein 7, also known as EGF-like protein 7, Multiple epidermal growth factor-like domains protein 7, Multiple EGF-like domains pr...
TMPY-02267 EGF Protein, Mouse, Recombinant (hFc)
EGF Protein, Mouse, Recombinant (hFc)
Mouse HEK293
EGF is the founding member of the EGF-family of proteins. Members of this protein family have highly similar structural and functional characteristics. EGF conta...
TMPY-02539 EGF Protein, Canine, Recombinant (His)
EGF Protein, Canine, Recombinant (His)
Canine E. coli
EGF is the founding member of the EGF-family of proteins. Members of this protein family have highly similar structural and functional characteristics. EGF conta...
BTC Protein, Mouse, Recombinant (His)
TMPJ-00058
Mouse Betacellulin is a single type I membrane protein which belongs to the EGF family of cytokines. EGF family has many members including EGF, TGF-a, Amphiregul...
NRG1 beta 1 Protein, Human, Recombinant (aa 2-246)
TMPJ-00448
Pro-neuregulin-1,Neuregulin-1 beta 1(NRG1) is a single-pass type I membrane protein and belongs to the neuregulin family .It contains 1 EGF-like domain and 1 Ig...
AREG Protein, Human, Recombinant
TMPJ-00859
Amphiregulin (AREG) is a single-pass membrane protein with 252 amino acids. AREG belongs to the amphiregulin family, which contains 1 EGF-like domain. AREG is ex...
TGF alpha Protein, Human, Recombinant (hFc)
TMPK-00757
Transforming growth factor-alpha (TGFA) has been proposed as a candidate gene in the etiology of nonsyndromic cleft lip with or without cleft palate (NS-CL/P) an...
AREG Protein, Human, Recombinant (hFc)
TMPK-00820
Amphiregulin (AREG) is a member of the epidermal growth factor (EGF) family and is expressed in a plethora of cancers. Tumour growth and metastasis were decrease...
AREG Protein, Mouse, Recombinant (hFc)
TMPK-00870
Amphiregulin (AREG) is a ligand of the epidermal growth factor receptor (EGFR), a widely expressed transmembrane tyrosine kinase. AREG is synthesized as a membra...
TGF alpha Protein, Mouse, Recombinant (hFc)
TMPK-00888
Transforming growth factor-alpha (TGFA) has been proposed as a candidate gene in the etiology of nonsyndromic cleft lip with or without cleft palate (NS-CL/P) an...
Neuregulin-1/NRG1 Protein, Human, Recombinant (His)
TMPY-00031
Neuregulin 1 or NRG1 is one of four proteins in the neuregulin family that act on the EGFR family of receptors. This growth factor was originally identified as a...
EGFL6 Protein, Mouse, Recombinant (His)
TMPY-00078
EGFL6, also known as EGF-L6, belongs to the epidermal growth factor (EGF) repeat superfamily. Members of this superfamily are characterized by the presence of EG...
EGFL6 Protein, Mouse, Recombinant (hFc)
TMPY-00094
EGFL6, also known as EGF-L6, belongs to the epidermal growth factor (EGF) repeat superfamily. Members of this superfamily are characterized by the presence of EG...
NRG3 Protein, Human, Recombinant (hFc)
TMPY-00192
NRG3 (Neuregulin 3) is a Protein Coding gene. NRG3 is a member of the neuregulin family of EGF proteins. It has been shown to activate the tyrosine phosphorylati...
EGF Protein, Mouse, Recombinant (His)
TMPY-00220
EGF is the founding member of the EGF-family of proteins. Members of this protein family have highly similar structural and functional characteristics. EGF conta...
RTN4RL1 Protein, Human, Recombinant (hFc)
TMPY-00343
RTN4RL1 Protein, Human, Recombinant (hFc) is expressed in HEK293 with hFc tag. The predicted molecular weight is 71.5 kDa. Accession number: Q86UN2
Neuregulin-1/NRG1 Protein, Human, Recombinant (hFc)
TMPY-00479
Neuregulin 1 or NRG1 is one of four proteins in the neuregulin family that act on the EGFR family of receptors. This growth factor was originally identified as a...
Betacellulin Protein, Mouse, Recombinant (His & hFc)
TMPY-01323
Betacellulin(BTC) is a member of the epidermal growth factor (EGF) family. These soluble proteins are ligands for one or more of the four receptor tyrosine kinas...
Epiregulin Protein, Mouse, Recombinant (hFc)
TMPY-02166
Epiregulin (EREG) is a member of the epidermal growth factor family. Epiregulin (EREG) can function as a ligand of EGFR (epidermal growth factor receptor), as we...
Epiregulin Protein, Human, Recombinant (hFc)
TMPY-02169
Epiregulin (EREG) is a member of the epidermal growth factor family. Epiregulin (EREG) can function as a ligand of EGFR (epidermal growth factor receptor), as we...
EGFL7 Protein, Mouse, Recombinant (His)
TMPY-02178
Epidermal growth factor-like protein 7, also known as EGF-like protein 7, Multiple epidermal growth factor-like domains protein 7, Multiple EGF-like domains pr...
EGF Protein, Mouse, Recombinant (hFc)
TMPY-02267
EGF is the founding member of the EGF-family of proteins. Members of this protein family have highly similar structural and functional characteristics. EGF conta...
EGF Protein, Canine, Recombinant (His)
TMPY-02539
EGF is the founding member of the EGF-family of proteins. Members of this protein family have highly similar structural and functional characteristics. EGF conta...
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