Dengue virus (DENV) is the cause of dengue fever. It is a mosquito-borne, single positive-stranded RNA virus of the family Flaviviridae, genus Flavivirus. The DENV genome is about 11000 bases of positive-sense, single-stranded RNA (ss RNA) that codes for three structural proteins (capsid protein C, membrane protein M, envelope protein E) and seven nonstructural proteins (NS1, NS2a, NS2b, NS3, NS4a, NS4b, NS5).The virus is transmitted to humans through the bites of infected female mosquitoes, though humans are not capable of transmitting the disease and are not contagious. There are no approved direct antiviral treatments for Dengue fever. Most antiviral drug research for Dengue infections has focussed on inhibition of the NS2B/NS3 protease or NS5 proteins. Reported protease inhibitor approaches have focussed mainly on targeted covalent inhibitors.
Cat No. | product name / Synonyms | Species | Expression System |
---|---|---|---|
TMPY-00047 | Dengue virus DENV-2 (Strain New Guinea C) Capsid protein/DENV-C Protein (His)
Dengue virus DENV-2 (Strain New Guinea C) Capsid protein/DENV-C Protein (His)
|
DENV | E. coli |
Dengue virus DENV-2 (Strain New Guinea C) Capsid protein/DENV-C Protein (His) is expressed in E. coli expression system with His tag. The predicted molecular wei... | |||
TMPY-00279 | Dengue virus DENV-2 (strain New Guinea C) NS5 (methyltransferase domain)/Nonstructural protein 5 Protein (His)
Dengue virus DENV-2 (strain New Guinea C) NS5 (methyltransferase domain)/Nonstructural protein 5 Protein (His)
|
DENV | E. coli |
Dengue virus DENV-2 (strain New Guinea C) NS5 (methyltransferase domain)/Nonstructural protein 5 Protein (His) is expressed in E. coli expression system with His... | |||
TMPY-04700 | Dengue virus (DENV) (type 2, strain New Guinea C/PUO-218 hybrid) E/Envelope Protein (aa 578-680, His)
Dengue virus (DENV) (type 2, strain New Guinea C/PUO-218 hybrid) E/Envelope Protein (aa 578-680, His)
|
DENV | P. pastoris (Yeast) |
Dengue virus (DENV) (type 2, strain New Guinea C/PUO-218 hybrid) E/Envelope Protein (aa 578-680, His) is expressed in yeast with His tag. The predicted molecular... | |||
TMPY-04800 | Dengue virus (DENV) (type 4, strain Philippines/H241/1956) E/Envelope Protein (His)
Dengue virus (DENV) (type 4, strain Philippines/H241/1956) E/Envelope Protein (His)
|
DENV | Baculovirus Insect Cells |
Dengue virus (DENV) (type 4, strain Philippines/H241/1956) E/Envelope Protein (His) is expressed in Baculovirus insect cells with His tag. The predicted molecula... | |||
TMPY-04883 | Dengue virus (DENV) (type 1, strain US/Hawaii/1944) DENV-NS1 Protein (His)
Dengue virus (DENV) (type 1, strain US/Hawaii/1944) DENV-NS1 Protein (His)
|
DENV | HEK293 Cells |
Dengue virus (DENV) (type 1, strain US/Hawaii/1944) DENV-NS1 Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is... | |||
TMPY-05023 | Dengue virus (DENV) (type 4, strain Philippines/H241/1956) NS1 Protein (His)
Dengue virus (DENV) (type 4, strain Philippines/H241/1956) NS1 Protein (His)
|
DENV | HEK293 Cells |
Dengue virus (DENV) (type 4, strain Philippines/H241/1956) NS1 Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight ... | |||
TMPY-05032 | Dengue virus (DENV) (type 1, strain US/Hawaii/1944) E/Envelope Protein (His)
Dengue virus (DENV) (type 1, strain US/Hawaii/1944) E/Envelope Protein (His)
|
DENV | Baculovirus Insect Cells |
Dengue virus (DENV) (type 1, strain US/Hawaii/1944) E/Envelope Protein (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weigh... | |||
TMPY-05311 | Dengue virus (DENV) (type 2, strain New Guinea C/PUO-218 hybrid) E/Envelope Protein (aa 281-679, T76R,Q77E,W101R,L107R,His)
Dengue virus (DENV) (type 2, strain New Guinea C/PUO-218 hybrid) E/Envelope Protein (aa 281-679, T76R,Q77E,W101R,L107R,His)
|
DENV | Baculovirus Insect Cells |
Dengue virus (DENV) (type 2, strain New Guinea C/PUO-218 hybrid) E/Envelope Protein (aa 281-679, T76R,Q77E,W101R,L107R,His) is expressed in Baculovirus insect ce... | |||
TMPY-05747 | DENV Envelope/DENV-E Protein (His)
DENV Envelope/DENV-E Protein (His)
|
DENV | HEK293 Cells |
DENV Envelope/DENV-E Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 12.4 kDa and the accession number is AC... | |||
TMPY-05821 | Dengue virus (DENV) (type 4, strain Philippines/H241/1956) E/Envelope Protein (aa 579-679, His)
Dengue virus (DENV) (type 4, strain Philippines/H241/1956) E/Envelope Protein (aa 579-679, His)
|
DENV | HEK293 Cells |
Dengue virus (DENV) (type 4, strain Philippines/H241/1956) E/Envelope Protein (aa 579-679, His) is expressed in HEK293 mammalian cells with His tag. The predicte... | |||
TMPY-06466 | Dengue virus (DENV) (type 3, strain Philippines/H87/1956) E/Envelope Protein (aa 579-678, His)
Dengue virus (DENV) (type 3, strain Philippines/H87/1956) E/Envelope Protein (aa 579-678, His)
|
DENV | Baculovirus Insect Cells |
Dengue virus (DENV) (type 3, strain Philippines/H87/1956) E/Envelope Protein (aa 579-678, His) is expressed in Baculovirus insect cells with His tag. The predict... | |||
TMPY-00052 | Dengue virus (DENV) (type 2, strain New Guinea C) NS1 Protein (His)
Dengue virus (DENV) (type 2, strain New Guinea C) NS1 Protein (His)
|
DENV | HEK293 Cells |
Dengue virus (DENV) (type 2, strain New Guinea C) NS1 Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 42.3 k... | |||
TMPY-04903 | Dengue virus (DENV) (type 3, strain Philippines/H87/1956) NS1 Protein (His)
Dengue virus (DENV) (type 3, strain Philippines/H87/1956) NS1 Protein (His)
|
DENV | HEK293 Cells |
Dengue virus (DENV) (type 3, strain Philippines/H87/1956) NS1 Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight i... | |||
TMPY-05824 | Dengue virus (DENV)(type 3, strain Philippines/H87/1956) E/Envelope Protein (aa 247-675, His)
Dengue virus (DENV)(type 3, strain Philippines/H87/1956) E/Envelope Protein (aa 247-675, His)
|
DENV | HEK293 Cells |
Dengue virus (DENV)(type 3, strain Philippines/H87/1956) E/Envelope Protein (aa 247-675, His) is expressed in HEK293 mammalian cells with His tag. The predicted ... | |||
TMPY-04689 | Dengue virus (DENV) (type 2, strain New Guinea C/PUO-218 hybrid) E/Envelope Protein (aa 247-675, His)
Dengue virus (DENV) (type 2, strain New Guinea C/PUO-218 hybrid) E/Envelope Protein (aa 247-675, His)
|
DENV | Baculovirus Insect Cells |
Dengue virus (DENV) (type 2, strain New Guinea C/PUO-218 hybrid) E/Envelope Protein (aa 247-675, His) is expressed in Baculovirus insect cells with His tag. The ... |