Shopping Cart

Remove All
Your shopping cart is currently empty

CHPG hydrochloride

Name: CHPG hydrochloride
Brand: TargetMol
SKU: T10809L
Price: 51 USD
Availability: InStock
Rating: 5 (10 reviews)

🥰Excellent

Catalog No. T10809L

Alias CHPG hydrochloride(170846-74-9 Free base)

CHPG hydrochloride is a selective agonist of mGluR5.

CHPG hydrochloride

🥰Excellent

Purity: 98.1%

Catalog No. T10809LAlias CHPG hydrochloride(170846-74-9 Free base)

CHPG hydrochloride is a selective agonist of mGluR5.

Pack Size	Price	Availability
1 mg	$51	In Stock
5 mg	$118	In Stock
10 mg	$177	In Stock
25 mg	$283	In Stock
50 mg	$403	In Stock
100 mg	$536	In Stock
200 mg	$728	In Stock
1 mL x 10 mM (in DMSO)	$103	In Stock

Add to Cart

Add to Quotation

Bulk & Custom

This molecule is a custom-made product. TargetMol has an excellent synthesis team with the experience and capability to provide you with cost-effective products. However, due to objective factors, there is a small probability that the synthesis may not be successful during the R&D process. We appreciate your understanding. If you have any questions, please feel free to contact us. We are committed to serving you wholeheartedly.

Questions

Batch Information

Select Batch

Purity:98.1%

Resource Download

COA HPLC HNMR

Product Introduction

Bioactivity

Description	CHPG hydrochloride is a selective agonist of mGluR5.
In vitro	After SO2 derivatives treatment, CHPG hydrochloride (10-500 µM) increases the cell viability and reduces the release of LDH. CHPG hydrochloride (0.5 mM) protects BV2 cells against SO2-induced apoptosis and increases the TSG-6 expression through the TSG-6/NF-κB pathway[1].
In vivo	In adult Sprague-Dawley male rats, injection of CHPG hydrochloride (250 nM) reduces significantly cerebral lesion volume by activation of the ERK and Akt signaling pathways[2].
Synonyms	CHPG hydrochloride(170846-74-9 Free base)

Chemical Properties

Molecular Weight	238.07
Formula	C₈H₉Cl₂NO₃
Smiles	O=C(C(C1=CC(O)=CC=C1Cl)N)O.Cl
Relative Density.	no data available
Color	White
Appearance	Solid

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 30 mg/mL (126.01 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	4.2004 mL	21.0022 mL	42.0045 mL	210.0223 mL
5 mM	0.8401 mL	4.2004 mL	8.4009 mL	42.0045 mL
10 mM	0.4200 mL	2.1002 mL	4.2004 mL	21.0022 mL
20 mM	0.2100 mL	1.0501 mL	2.1002 mL	10.5011 mL
50 mM	0.0840 mL	0.4200 mL	0.8401 mL	4.2004 mL
100 mM	0.0420 mL	0.2100 mL	0.4200 mL	2.1002 mL

Calculator

Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Molecular Weight Calculator

In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Sci Citations

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc