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TargetMol | Compound Library

Hematonosis Compound Library

Catalog No. L8400

Hematologic diseases (hematonosis), disorders of the blood and blood-forming organs, afflict millions of Americans. In addition to hematological malignancies, such as leukemia and lymphomas, children and adolescents can suffer blood disorder, that are not classified as cancer, but may lead to severe diseases and therefore require treatment. These blood disorders include severe aplastic anemia (SAA), thalassemia, immune (idiopathic) thrombocytopenic purpura, congenital neutropenia, hemophilia, sickle-cell disease, iron deficiency anemia and various other diseases. In the past, due to the lack of effective treatments, many diseases have been called "incurable diseases". In recent years, with in-depth development of medical research, the treatment of blood diseases has been significantly improved. Modern medicine uses hormones, chemotherapy and other methods for the treatment of blood diseases, but the side effects are large, and the patient has a low cure rate and is prone to recurrence. Bone marrow transplantation for the treatment of leukemia was introduced then the cure rate of leukemia was improved. However, the bone marrow resources were very scarce, and a large part of the donated bone marrow was inconsistent with the patient's HLA, even if the transplant was successful, and the recurrence rate was as high as 70% within 5 years. Therefore, it is necessary to develop new therapies and drugs for the treatment of hematologic diseases. Hematonosis Compound Library from TargetMol provides you with compounds related to hematologic diseases that can be used for high throughput and high content screening.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.

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Catalog No. L8400

Hematonosis Compound Library

sizeIn stock

  • 1 mg
  • 30 μL x 10 mM (in DMSO)
  • 50 μL x 10 mM (in DMSO)
  • 100 μL x 10 mM (in DMSO)
  • 250 μL x 10 mM (in DMSO)
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Product Description Product Description

  • A unique collection of 2405 compounds related to hematologic diseases for high throughput screening (HTS) and high content screening (HCS);
  • Effective tool for research in functions of the hematologic system and related diseases, such as hemophilia, leukemia, β-thalassemia;
  • Detailed compound information with structure, target, activity, IC50 value, and biological activity description;
  • NMR and HPLC/LCMS validated to ensure high purity and quality;

Packaging And Storage Packaging And Storage

  • Powder or pre-dissolved DMSO solutions in 96/384 well plate with optional 2D barcode
  • Shipped with blue ice
  • This compound library is provided at a concentration of 10 mM in DMSO. A small number of compounds may be provided in different solvents or concentrations due to solubility or stability requirements. Please refer to the specific product information for details.

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Apoptosis
NF-κB
Autophagy
PI3K
EGFR
HDAC
Wnt/beta-catenin
mTOR
JAK
Akt
STAT
FLT
AMPK
GSK-3
Antibacterial
VEGFR
Endogenous Metabolite
Bcl-2 Family
CDK
c-Kit
Proteasome
Bcr-Abl
PDGFR
HIF/HIF Prolyl-Hydroxylase
Histone Methyltransferase
Src
HIF
ERK
Dehydrogenase
COX
Tyrosine Kinases
Potassium Channel
DNA/RNA Synthesis
Hedgehog/Smoothened
Antibiotic
FGFR
S6 Kinase
HIV Protease
DNA-PK
Reactive Oxygen Species
Caspase
TNF
Epigenetic Reader Domain
p38 MAPK
Parasite
ATM/ATR
HER
DNA Methyltransferase
Topoisomerase
PKC
PARP
IL Receptor
PDK
Pim
JNK
c-Met/HGFR
Mitophagy
Aurora Kinase
Ferroptosis
PPAR
c-RET
Microtubule Associated
Influenza Virus
PD-1/PD-L1
Gamma-secretase
c-Myc
BTK
ALK
Raf
MEK
Antifungal
Virus Protease
TAM Receptor
MAPK
Cytochromes P450
IGF-1R
DPP-4
CXCR
PI4K
p53
Nrf2
PKA
Calcium Channel
E1/E2/E3 Enzyme
Nucleoside Antimetabolite/Analog
c-Fms
Histone Demethylase
Syk
Trk receptor
NO Synthase
Smo
Casein Kinase
Antiviral
Chk
Antioxidant
AChR
Interleukin
Lipoxygenase
HCV Protease
IκB/IKK
Phosphatase
Beta Amyloid
Isocitrate Dehydrogenase (IDH)
PLK
TLR
MMP
Drug Metabolite
PDE
HSP
P-gp
ROS
Sodium Channel
Adenosine Receptor
NOS
CSF-1R
SIK
FAK
Mitochondrial Metabolism
Antifection
5-HT Receptor
PTEN
ROCK
Histone Acetyltransferase
DYRK
Prostaglandin Receptor
DUB
Cysteine Protease
MELK
GABA Receptor
Anti-infection
HSV
IRAK
TGF-beta/Smad
DNA Alkylation
Rho
Cannabinoid Receptor
IAP
transporter
ROS Kinase
Retinoid Receptor
Aminopeptidase
SARS-CoV
Tyrosinase
Integrin
Sirtuin
Adrenergic Receptor
HBV
Mdm2
DNA Alkylator/Crosslinker
Ras
IRE1
Porcupine
Carbonic Anhydrase
Estrogen/progestogen Receptor
Cholinesterase (ChE)
GluR
CaMK
ATPase
Immunology/Inflammation related
MNK
Glucosidase
Histamine Receptor
S1P Receptor
SGK
ADC Cytotoxin
LDL
Tie-2
BCRP
DHFR
Adenosine Deaminase
RAAS
NOD-like Receptor (NLR)
ACK1
Serine/threonin kinase
Methionine Adenosyltransferase (MAT)
IFNAR
Reverse Transcriptase
MLK
PAK
Dopamine Receptor
GTPase
LTR
Lipid
Chloride channel
PGE Synthase
Ephrin Receptor
Opioid Receptor
Thrombin
TRP/TRPV Channel
NOD
Kinesin
BACE
UGT
KSP
NEDD8
CRM1
Leukotriene Receptor
Monoamine Transporter
Cholecystokinin Receptor
RIP kinase
Survivin
Hippo pathway
SGLT
GRK
TOPK
Discoidin Domain Receptor (DDR)
Phospholipase
CRISPR/Cas9
ATP Citrate Lyase
Antifolate
Fatty Acid Synthase
Acyltransferase
Aryl Hydrocarbon Receptor
Hck
Liver X Receptor
Transferase
GPCR
Glutathione Peroxidase
AhR
Estrogen Receptor/ERR
NAMPT
Serine Protease
PYK2
NADPH
Androgen Receptor
MAO
Beta-Secretase
PERK
cAMP
NMDAR
CCR
NADPH-oxidase
Glucocorticoid Receptor
Lipase
YAP
MyD88
RSV
RAR/RXR
PKM
Wee1
Haspin Kinase
MRP
ROR
BMI-1
DAPK
LPL Receptor
Platelet aggregation
Free radical scavengers
Reductase
Neprilysin
Cuproptosis
Glucokinase
NPC1L1
MALT
Proton pump
Guanylate cyclase
Glutaminase
Monocarboxylate transporter
NUDIX hydrolase
Factor Xa
Imidazoline Receptor
CFTR
p97
Na+/Ca2+ Exchanger
MicroRNA
LRRK2
ABC Transporter
PROTACs
PAD
FAAH
DNA
Protease-activated Receptor
FXR
OXPHOS
hCE
KLF
Adenylyl Cyclase
Myosin
STING
Melanin-concentrating Hormone Receptor (MCHR)
Decarboxylase
Aromatase
OCT
Telomerase
Protease
Amino Acids and Derivatives
GST
Progesterone Receptor
Sigma receptor
Arginase
DNA gyrase
gp120/CD4
Thrombopoietin Receptor