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TargetMol | Compound Library

Hematonosis Compound Library

Catalog No. L8400

Hematologic diseases (hematonosis), disorders of the blood and blood-forming organs, afflict millions of Americans. In addition to hematological malignancies, such as leukemia and lymphomas, children and adolescents can suffer blood disorder, that are not classified as cancer, but may lead to severe diseases and therefore require treatment. These blood disorders include severe aplastic anemia (SAA), thalassemia, immune (idiopathic) thrombocytopenic purpura, congenital neutropenia, hemophilia, sickle-cell disease, iron deficiency anemia and various other diseases. In the past, due to the lack of effective treatments, many diseases have been called "incurable diseases". In recent years, with in-depth development of medical research, the treatment of blood diseases has been significantly improved. Modern medicine uses hormones, chemotherapy and other methods for the treatment of blood diseases, but the side effects are large, and the patient has a low cure rate and is prone to recurrence. Bone marrow transplantation for the treatment of leukemia was introduced then the cure rate of leukemia was improved. However, the bone marrow resources were very scarce, and a large part of the donated bone marrow was inconsistent with the patient's HLA, even if the transplant was successful, and the recurrence rate was as high as 70% within 5 years. Therefore, it is necessary to develop new therapies and drugs for the treatment of hematologic diseases.

Hematonosis Compound Library from TargetMol provides you with compounds related to hematologic diseases that can be used for high throughput and high content screening.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.

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Catalog No. L8400

Hematonosis Compound Library

sizeIn stock

  • 1 mg
  • 30 μL x 10 mM (in DMSO)
  • 50 μL x 10 mM (in DMSO)
  • 100 μL x 10 mM (in DMSO)
  • 250 μL x 10 mM (in DMSO)
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Product Description Product Description

  • A unique collection of 2405 compounds related to hematologic diseases for high throughput screening (HTS) and high content screening (HCS);
  • Effective tool for research in functions of the hematologic system and related diseases, such as hemophilia, leukemia, β-thalassemia;
  • Detailed compound information with structure, target, activity, IC50 value, and biological activity description;
  • NMR and HPLC/LCMS validated to ensure high purity and quality;

Packaging And Storage Packaging And Storage

  • Powder or pre-dissolved DMSO solutions in 96/384 well plate with optional 2D barcode
  • Shipped with blue ice
  • This compound library is provided at a concentration of 10 mM in DMSO. A small number of compounds may be provided in different solvents or concentrations due to solubility or stability requirements. Please refer to the specific product information for details.

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Apoptosis
Autophagy
NF-κB
PI3K
EGFR
Wnt/beta-catenin
Akt
mTOR
HDAC
JAK
STAT
Endogenous Metabolite
FLT
Antibacterial
AMPK
Bcl-2 Family
GSK-3
VEGFR
HIF/HIF Prolyl-Hydroxylase
CDK
c-Kit
ROS
Proteasome
Bcr-Abl
ERK
PDGFR
Src
Histone Methyltransferase
COX
p38 MAPK
DNA/RNA Synthesis
Caspase
Dehydrogenase
Parasite
HIF
Reactive Oxygen Species
Potassium Channel
Antibiotic
HIV Protease
TNF
S6 Kinase
Tyrosine Kinases
Hedgehog/Smoothened
Interleukin
FGFR
DNA-PK
JNK
Epigenetic Reader Domain
PARP
ATM/ATR
Virus Protease
DNA Methyltransferase
HER
PKC
NO Synthase
Ferroptosis
c-Met/HGFR
Topoisomerase
PPAR
PDK
c-Myc
PD-1/PD-L1
Mitophagy
Aurora Kinase
Microtubule Associated
Antifungal
Gamma-secretase
IL Receptor
Pim
IGF-1R
c-RET
BTK
Cytochromes P450
Influenza Virus
ALK
Raf
MEK
MAPK
Smo
Isocitrate Dehydrogenase (IDH)
Nrf2
Nucleoside Antimetabolite/Analog
Beta Amyloid
c-Fms
PI4K
Calcium Channel
TAM Receptor
MDM-2/p53
Histone Demethylase
CXCR
DPP-4
Ras
PKA
E1/E2/E3 Enzyme
Casein Kinase
Phosphatase
TLR
p53
MMP
Trk receptor
SARS-CoV
IκB/IKK
Syk
AChR
Antiviral
Antioxidant
HSV
PDE
Chk
TGF-beta/Smad
Lipoxygenase
P-gp
PLK
HSP
Drug Metabolite
HCV Protease
Adenosine Receptor
Histone Acetyltransferase
Sodium Channel
NOS
Mitochondrial Metabolism
FAK
DYRK
ROCK
5-HT Receptor
Anti-infection
PTEN
CSF-1R
SIK
Antifection
GABA Receptor
ROS Kinase
IAP
Sirtuin
Cysteine Protease
OXPHOS
Tyrosinase
DUB
Rho
MELK
Reverse Transcriptase
IRAK
Bcl-6
TRP/TRPV Channel
Adrenergic Receptor
CaMK
ATPase
DNA Alkylator/Crosslinker
Prostaglandin Receptor
Retinoid Receptor
Cannabinoid Receptor
Serine Protease
Integrin
Tie-2
DNA Alkylation
Survivin
Aminopeptidase
Mdm2
transporter
SGK
NOD-like Receptor (NLR)
HBV
Cholinesterase (ChE)
Porcupine
Aryl Hydrocarbon Receptor
IRE1
Immunology/Inflammation related
Reductase
Estrogen Receptor/ERR
Glucosidase
Estrogen/progestogen Receptor
Kinesin
Thrombin
Monoamine Oxidase
PROTACs
Carbonic Anhydrase
PERK
GluR
MLK
Amino Acids and Derivatives
MNK
S1P Receptor
Histamine Receptor
Dopamine Receptor
PGE Synthase
ADC Cytotoxin
GPCR
GTPase
NAMPT
MAO
PAK
Ephrin Receptor
NOD
BACE
IFNAR
ACK1
Lipid
LTR
Monoamine Transporter
glycosidase
ATP Citrate Lyase
Hippo pathway
Chloride channel
MyD88
Glutathione Peroxidase
Serine/threonin kinase
LDL
Opioid Receptor
FKBP
DHFR
RAAS
Acyltransferase
Adenosine Deaminase
CRM1
Antifolate
RIP kinase
UGT
Fatty Acid Synthase
Thrombopoietin Receptor
BCRP
Methionine Adenosyltransferase (MAT)
IKZF
Liver X Receptor
cAMP
Transferase
NADPH
Hck
RANKL/RANK
GRK
Telomerase
SGLT
AhR
NEDD8
CCR
CRISPR/Cas9
Proton pump
Monocarboxylate transporter
Leukotriene Receptor
FXR
KSP
Cadherin
STING
Pyroptosis
Lipase
NMDAR
Angiotensin-converting Enzyme (ACE)
TOPK
Cholecystokinin Receptor
Myosin
Beta-Secretase
Phospholipase
LPL Receptor
PYK2
Androgen Receptor
Wee1
Cuproptosis
Discoidin Domain Receptor (DDR)
DAPK
PGK1
Y Box Binding Protein 1
Arginase
Na+/Ca2+ Exchanger
gp120/CD4
Factor Xa
Progesterone Receptor
AIM2
GST
Aromatase
Platelet aggregation
NUDIX hydrolase
YAP
Necroptosis
OCT
Glucocorticoid Receptor
Na-K-Cl cotransporter
hCE
BMI-1
CD38
NR4A
ABC Transporter
FAAH
DNA
CD74
Kras
Hydroxylase
Sigma receptor
CFTR
Imidazoline Receptor
RAR/RXR
MALT
Prolyl Endopeptidase (PREP)
FABP
DNA gyrase
Guanylate cyclase
LRRK2
Free radical scavengers
NADPH-oxidase
PKM
MicroRNA
ROR
Glucokinase
PAFR
Haspin Kinase
RSV
Protease
KLF
Melanin-concentrating Hormone Receptor (MCHR)
NPC1L1
Decarboxylase
Neprilysin
Liposome
Adenylyl Cyclase
MRP
Glutaminase
PAD
Urea Transporter
Protease-activated Receptor
p97
Ferroportin

Keywords