EphB4 Protein, Mouse, Recombinant (hFc)

Catalog No. TMPY-01786 Copy Product Info

EphB4 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 84.7 kDa and the accession number is P54761-1.

EphB4 Protein, Mouse, Recombinant (hFc)

Catalog No. TMPY-01786

Copy Product Info

EphB4 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 84.7 kDa and the accession number is P54761-1.

Pack Size	Price	USA Stock	Global Stock
5 μg	$30	7-10 days	7-10 days
10 μg	$41	7-10 days	7-10 days
20 μg	$63	7-10 days	7-10 days
50 μg	$117	7-10 days	7-10 days
100 μg	$192	7-10 days	7-10 days
200 μg	$320	-	In Stock

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In stock · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

For research use only—not for human use. No sales to individuals. Use as intended only.

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Biological Activity	Measured by its binding ability in a functional ELISA. Immobilized Mouse Ephrin B2 His at 2 μg/ml (100 μl/well) can bind Mouse EphB4 hFc , the EC50 of Mouse EphB4 hFc is 2.0-10.0 ng/mL.
Description	EphB4 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 84.7 kDa and the accession number is P54761-1.
Species	Mouse
Expression System	HEK293 Cells
Tag	C-hFc
Accession Number	P54761-1
Synonyms	Tyro11,Myk1,MDK2,Htk,EPH receptor B4,AI042935
Construction	A DNA sequence encoding the mouse EPHB4 (P54761-1) extracellular domain (Met 1-Ala 539) was fused with the Fc region of human IgG1 at the C-terminus. Predicted N terminal: Leu 16
Protein Purity	> 97 % as determined by SDS-PAGE
Molecular Weight	84.7 kDa (predicted); 110 kDa (reducing condition, due to glycosylation)
Endotoxin	< 1.0 EU/μg of the protein as determined by the LAL method.
Formulation	Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4. Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization.
Reconstitution	Reconstituted with 20 mM Tris, 150 mM NaCl, pH 7.5 to 0.25 mg/mL. Reconstitution conditions may vary depending on the lot.
Stability & Storage	It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
Shipping	In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
Research Background	Ephrin type-B receptor 4 is a protein that in humans is encoded by the EPHB4 gene. It is a single-pass type I membrane protein belonging to the ephrin receptor subfamily of protein kinase superfamily. Members of the ephrin and Eph family are local mediators of cell function through largely contact-dependent processes in development and in maturity. Furthermore, EphB4 protein and the corresponding ligand Ephrin-B2 contribute to tumor growth in various human tumors. EphB4 protein has tumor suppressor activities and that regulation of cell proliferation, extracellular matrix remodeling, and invasive potential are important mechanisms of tumor suppression. Therefore, Ephrin-B2/EphB4 may be recognized as a novel prognostic indicator for cancers.