store at low temperature,keep away from direct sunlight
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Tracazolate hydrochloride (Tracazolate (hydrochloride)) is a modulator of the GABAA receptor with anxiolytic and anticonvulsant activity. Tracazolate hydrochloride potentiates α1β1γ2s and α1β3γ2 with EC50s of 13.2 μM and 1.5 μM.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
2 mg | In stock | $ 36.00 | |
5 mg | In stock | $ 59.00 | |
10 mg | In stock | $ 96.00 | |
25 mg | In stock | $ 197.00 | |
50 mg | In stock | $ 328.00 | |
100 mg | In stock | $ 493.00 |
Description | Tracazolate hydrochloride (Tracazolate (hydrochloride)) is a modulator of the GABAA receptor with anxiolytic and anticonvulsant activity. Tracazolate hydrochloride potentiates α1β1γ2s and α1β3γ2 with EC50s of 13.2 μM and 1.5 μM. |
In vitro | Tracazolate hydrochloride (10 μM) enhanced the sensitivity of α1β2δ-containing GABAA receptors and increased the maximum current amplitude in oocytes [1]. Tracazolate hydrochloride inhibited α1β1ε, α1β3ε, α1β3, and α6β3γ with EC50s of 4.0 μM, 1.2 μM, 2.7 μM, and 1.1 μM. Tracazolate hydrochloride interacted with γ-aminobutyric acid GABAA receptors, adenosine receptors, and phosphodiesterases [2]. |
Synonyms | Tracazolate (hydrochloride) |
Molecular Weight | 340.85 |
Formula | C16H25ClN4O2 |
CAS No. | 1135210-68-2 |
store at low temperature,keep away from direct sunlight
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 100 mg/mL (293.4 mM), Sonication is recommended.
1eq. HCl: < 34.09 mg/mL
You can also refer to dose conversion for different animals. More
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Tracazolate hydrochloride 1135210-68-2 Membrane transporter/Ion channel Neuroscience GABA Receptor Tracazolate Tracazolate (hydrochloride) Tracazolate Hydrochloride inhibitor inhibit