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Suritozole

🥰Excellent
Catalog No. T8568Cas No. 110623-33-1
Alias MDL-26479

Suritozole (MDL-26479) is a negative modulator at the gamma-aminobutyric acidA (GABAA) receptor

Suritozole

Suritozole

🥰Excellent
Purity: 99.25%
Catalog No. T8568Alias MDL-26479Cas No. 110623-33-1
Suritozole (MDL-26479) is a negative modulator at the gamma-aminobutyric acidA (GABAA) receptor
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
1 mg$56In StockIn Stock
5 mg$125In StockIn Stock
10 mg$190In StockIn Stock
25 mg$313In StockIn Stock
50 mg$441In StockIn Stock
100 mg$596In StockIn Stock
200 mg$791-In Stock
1 mL x 10 mM (in DMSO)$112In StockIn Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Purity:99.25%
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Product Introduction

Bioactivity
Description
Suritozole (MDL-26479) is a negative modulator at the gamma-aminobutyric acidA (GABAA) receptor
In vivo
Suritozole is a negative modulator at the gamma-aminobutyric acidA (GABAA) receptor that enhances cholinergic function, in attenuating spatial memory deficits after traumatic brain injury in the rat.
SynonymsMDL-26479
Chemical Properties
Molecular Weight223.27
FormulaC10H10FN3S
Cas No.110623-33-1
SmilesCN1C(=NN(C)C1=S)C2=CC(F)=CC=C2
Relative Density.no data available
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 27.5 mg/mL (123.17 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM4.4789 mL22.3944 mL44.7888 mL223.9441 mL
5 mM0.8958 mL4.4789 mL8.9578 mL44.7888 mL
10 mM0.4479 mL2.2394 mL4.4789 mL22.3944 mL
20 mM0.2239 mL1.1197 mL2.2394 mL11.1972 mL
50 mM0.0896 mL0.4479 mL0.8958 mL4.4789 mL
100 mM0.0448 mL0.2239 mL0.4479 mL2.2394 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
1 Enter information below:
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2 Enter the in vivo formulation:
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

SuritozoleMDL26479MDL 26479GABAReceptorGABAAGABA Receptor
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