Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Selpercatinib (LOXO-292) is a tyrosine kinase inhibitor with antineoplastic properties(IC50 of 14.0 nM, 24.1 nM, and 530.7 nM for RET (WT), RET (V804M) , and RET (G810R), respectively)
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
2 mg | In stock | $ 30.00 | |
5 mg | In stock | $ 47.00 | |
10 mg | In stock | $ 80.00 | |
25 mg | In stock | $ 178.00 | |
50 mg | In stock | $ 288.00 | |
100 mg | In stock | $ 531.00 | |
200 mg | In stock | $ 768.00 | |
500 mg | In stock | $ 1,150.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 54.00 |
Description | Selpercatinib (LOXO-292) is a tyrosine kinase inhibitor with antineoplastic properties(IC50 of 14.0 nM, 24.1 nM, and 530.7 nM for RET (WT), RET (V804M) , and RET (G810R), respectively) |
Targets&IC50 | RET (WT):14.0 nM , RET (G810R):530.7 nM, RET (V804M):24.1 nM |
Synonyms | LOXO-292 |
Molecular Weight | 525.6 |
Formula | C29H31N7O3 |
CAS No. | 2152628-33-4 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 8.33 mg/mL (15.85 mM), sonification is recommended.
You can also refer to dose conversion for different animals. More
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Selpercatinib 2152628-33-4 Apoptosis Tyrosine Kinase/Adaptors c-RET FVB/NRj mice RET (WT) inhibit Inhibitor RET (G810R) RET (V804M) LOXO 292 LOXO292 RET anticancer LOXO-292 inhibitor