Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Sari 59-801 is a novel, orally effective hypoglycemic compound that appears to act largely by stimulation of insulin release. SARI-59-801 was more potent in producing hypoglycemia (ED25 = 47 mg/kg) than their lean littermates (ED25 = 131 mg/kg).
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 86.00 | |
5 mg | In stock | $ 319.00 | |
10 mg | In stock | $ 498.00 | |
25 mg | In stock | $ 812.00 | |
50 mg | In stock | $ 1,130.00 | |
100 mg | In stock | $ 1,520.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 323.00 |
Description | Sari 59-801 is a novel, orally effective hypoglycemic compound that appears to act largely by stimulation of insulin release. SARI-59-801 was more potent in producing hypoglycemia (ED25 = 47 mg/kg) than their lean littermates (ED25 = 131 mg/kg). |
In vivo | The 2-hr hypoglycemic ED25 in fasting mice was 110 mg/kg; the plasma insulin levels were increased, with an ED50 of 47 mg/kg. The significant hypoglycemic activity was observed 2 hr after oral administration of 59-801 to fasting rats (ED25 = 86 mg/kg), while plasma insulin was elevated by 62% at 100 mg/kg. |
Synonyms | Sari-59-801 |
Molecular Weight | 313.39 |
Formula | C18H23N3O2 |
CAS No. | 80565-58-8 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 65 mg/mL (207.41 mM)
You can also refer to dose conversion for different animals. More
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