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Ralitoline

Catalog No. T28503 CAS 1089085-40-4

Synonyms: GOE-4942, PD-117818, Ralitolina, CI-946, Ralitolinum

Ralitoline (Ralitolinum) is an anticonvulsant with anticancer activity and sodium channel blocking activity.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.

Ralitoline, CAS 1089085-40-4

Pack Size	Availability	Price/USD
1 mg	In stock	$ 130.00
5 mg	In stock	$ 320.00
10 mg	In stock	$ 480.00
25 mg	In stock	$ 786.00
50 mg	In stock	$ 1,080.00
100 mg	In stock	$ 1,480.00
500 mg	In stock	$ 2,960.00

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Purity: 98.73%

Biological Description

Chemical Properties

Storage & Solubility Information

Description

Ralitoline (Ralitolinum) is an anticonvulsant with anticancer activity and sodium channel blocking activity.

Synonyms	GOE-4942, PD-117818, Ralitolina, CI-946, Ralitolinum
Molecular Weight	296.77
Formula	C13H13ClN2O2S
CAS No.	1089085-40-4

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 55 mg/mL (185.33 mM)

References and Literature

1. Dostal LA, et al. Developmental toxicity study in rats treated with the anticonvulsant, ralitoline. Teratology. 1995 ; 51(1):11-19. 2. Fischer W, et al. Anticonvulsant and sodium channel blocking effects of ralitoline in different screening models. Naunyn Schmiedebergs Arch Pharmacol. 1992 ; 346(4):442-452. 3. Löscher W, et al. Ralitoline: a reevaluation of anticonvulsant profile and determination of "active" plasma concentrations in comparison with prototype antiepileptic drugs in mice. Epilepsia. 1991 ; 32(4):560-568. 4. Rock DM, et al. Ralitoline (CI-946) and CI-953 block sustained repetitive sodium action potentials in cultured mouse spinal cord neurons and displace batrachotoxinin A 20-alpha-benzoate binding in vitro. Epilepsy Res. 1991 ; 8(3):197-203.

Related compound libraries

This product is contained In the following compound libraries：

Membrane Protein-targeted Compound Library Anti-Cancer Active Compound Library Anti-Cancer Compound Library Bioactive Compound Library Bioactive Compounds Library Max

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

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What is the mass of compound required to make a 10 mM stock solution in 10 ml of water given that the molecular weight of the compound is 197.13 g/mol?
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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

Ralitoline 1089085-40-4 GOE-4942 PD-117818 CI946 GOE4942 Ralitolina CI-946 PD117818 CI 946 Ralitolinum GOE 4942 PD 117818 inhibitor inhibit

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