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Proglumide

Catalog No. T1052 CAS 6620-60-6

Synonyms: Xylamide, Binoside

Proglumide is a cholecystokinin antagonist, which blocks both the CCKA and CCKB subtypes. Proglumide is a drug that exerts an inhibitory effect on gastric secretion and reduces gastrointestinal motility. It is used clinically in the drug therapy of gastrointestinal ulcers.

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Proglumide, CAS 6620-60-6

Pack Size	Availability	Price/USD
25 mg	In stock	$ 34.00
50 mg	In stock	$ 48.00
100 mg	In stock	$ 93.00
200 mg	In stock	$ 121.00
1 mL * 10 mM (in DMSO)	In stock	$ 54.00

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Purity: 99.44%

Biological Description

Chemical Properties

Storage & Solubility Information

Description

Synonyms	Xylamide, Binoside
Molecular Weight	334.42
Formula	C18H26N2O4
CAS No.	6620-60-6

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 2 years

Solubility Information

DMSO: 55 mg/mL (164.47 mM)

( < 1 mg/ml refers to the product slightly soluble or insoluble )

References and Literature

1. Bunney BS,et al. Ann N Y Acad Sci. 1985;448:345-51.

Related compound libraries

This product is contained In the following compound libraries：

Human Metabolite Library FDA-Approved & Pharmacopeia Drug Library Anti-Cancer Drug Library NMPA-Approved Drug Library Oxidation-Reduction Compound Library Inhibitor Library Neuronal Signaling Compound Library Approved Drug Library Anti-Obesity Compound Library Neurotransmitter Receptor Compound Library

Related Products

Related compounds with same targets

Spiroglumide GV-150013X GV150013 XL413 hydrochloride Nastorazepide PHA-767491 Lorglumide sodium salt N-Cbz-DL-tryptophan

Dose Conversion

You can also refer to dose conversion for different animals. More

In vivo Formulation Calculator (Clear solution)

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Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

Note:

Be sure to add the solvent(s) in order. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.

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An example of a molarity calculation using the molarity calculator
What is the mass of compound required to make a 10 mM stock solution in 10 ml of water given that the molecular weight of the compound is 197.13 g/mol?
Enter 197.13 into the Molecular Weight (MW) box
Enter 10 into the Concentration box and select the correct unit (millimolar)
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The answer of 19.713 mg appears in the Mass box

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An example of a dilution calculation using the Tocris dilution calculator
What volume of a given 10 mM stock solution is required to make 20ml of a 50 μM solution?
Using the equation C1V1 = C2V2, where C1=10 mM, C2=50 μM, V2=20 ml and V1 is the unknown:
Enter 10 into the Concentration (start) box and select the correct unit (millimolar)
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The answer of 100 microliter (0.1 ml) appears in the Volume (start) box

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Molecule Formula

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Definitions of molecular mass, molecular weight, molar mass and molar weight:
Molecular mass (molecular weight) is the mass of one molecule of a substance and is expressed n the unified atomic mass units (u). (1 u is equal to 1/12 the mass of one atom of carbon-12)
Molar mass (molar weight) is the mass of one mole of a substance and is expressed in g/mol.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

Proglumide 6620-60-6 GPCR/G Protein cholecystokinin SOD TBARS CCK-A CNS antiepileptic secretion Xylamide CAT CCK Receptor CCK-B Binoside inhibit GSH Cholecystokinin Receptor GST antioxidant gastric Inhibitor inhibitor

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