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Penicillin V Potassium

Name: Penicillin V Potassium
Brand: TargetMol
SKU: T1126
Price: 29 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T1126Cas No. 132-98-9

Alias Phenoxymethylpenicillin potassium salt, Penicillin V potassium salt

Penicillin V Potassium (Phenoxymethylpenicillin potassium salt) is an orally administered, broad-spectrum penicillin antibiotic used for treating mild to moderate infections caused by susceptible gram-positive organisms.

Penicillin V Potassium

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Purity: 97.71%

Catalog No. T1126Alias Phenoxymethylpenicillin potassium salt, Penicillin V potassium saltCas No. 132-98-9

Pack Size	Price	USA Warehouse	Global Warehouse	Quantity
100 mg	$29	In Stock	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Batch Information

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Purity:97.71%

Appearance:Solid

Color:White

Resource Download

COA HNMR LCMS

Product Introduction

Penicillin V Potassium AI Summary

Penicillin V Potassium exhibits multiple bioactivities. It acts as an antagonist of thyroid hormone receptor beta signaling with a potency of 35.5 nM and as an agonist of the antioxidant response element (ARE) signaling pathway with a potency of 38570.8 nM. Additionally, Penicillin V Potassium significantly inhibits sodium fluorescein uptake in OATP1B3-transfected CHO cells with an inhibition rate of 108.77%, and in OATP1B1-transfected CHO cells with an inhibition rate of 91.66%. It demonstrates antiviral activity by inhibiting SARS-CoV-2 induced cytotoxicity in both Caco-2 cells with an inhibition rate of -1.63% at 10 µM concentration and in VERO-6 cells with an inhibition rate of 0.29% at the same concentration after 48 hours. The compound also inhibits the SARS-CoV-2 3CL-Pro protease by 27.04% at a concentration of 20 µM..

Note: Summary generated by AI. Data source: ChEMBL

Bioactivity

Description	Penicillin V Potassium (Phenoxymethylpenicillin potassium salt) is an orally administered, broad-spectrum penicillin antibiotic used for treating mild to moderate infections caused by susceptible gram-positive organisms.
Synonyms	Phenoxymethylpenicillin potassium salt, Penicillin V potassium salt

Chemical Properties

Molecular Weight	388.48
Formula	C₁₆H₁₇KN₂O₅S
Cas No.	132-98-9
Smiles	[K+].CC1(C)S[C@@H]2[C@H](NC(=O)COc3ccccc3)C(=O)N2[C@H]1C([O-])=O
Relative Density.	1.4

Storage & Solubility Information

Storage

In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

H2O: 110 mg/mL (283.15 mM), Sonication and heating are recommended.

DMSO: 1 mg/mL (2.57 mM), Sonication is recommended.

In Vivo Formulation

10% DMSO+40% PEG300+5% Tween 80+45% Saline: 1 mg/mL (2.57 mM), Sonication is recommended.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

DMSO/H2O

	1mg	5mg	10mg	50mg
1 mM	2.5741 mL	12.8707 mL	25.7414 mL	128.7068 mL

H2O

	1mg	5mg	10mg	50mg
5 mM	0.5148 mL	2.5741 mL	5.1483 mL	25.7414 mL
10 mM	0.2574 mL	1.2871 mL	2.5741 mL	12.8707 mL
20 mM	0.1287 mL	0.6435 mL	1.2871 mL	6.4353 mL
50 mM	0.0515 mL	0.2574 mL	0.5148 mL	2.5741 mL
100 mM	0.0257 mL	0.1287 mL	0.2574 mL	1.2871 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc