Powder: -20°C for 3 years | In solvent: -80°C for 1 year
PFI-2 is an effective, specific and cell-active lysine methyltransferase SETD7 inhibitor (Ki/IC50: 0.33/2 nM), 1000-fold selectivity over other methyltransferases and other non-epigenetic targets.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
5 mg | 4-6 weeks | $ 83.00 | |
10 mg | 4-6 weeks | $ 131.00 | |
25 mg | 4-6 weeks | $ 254.00 | |
50 mg | 4-6 weeks | $ 448.00 | |
100 mg | 4-6 weeks | $ 807.00 |
Description | PFI-2 is an effective, specific and cell-active lysine methyltransferase SETD7 inhibitor (Ki/IC50: 0.33/2 nM), 1000-fold selectivity over other methyltransferases and other non-epigenetic targets. |
Targets&IC50 | SETD7:2 nM |
Synonyms | PFI2, PFI 2, (R)-PFI-2 |
Molecular Weight | 499.52 |
Formula | C23H25F4N3O3S |
CAS No. | 1627676-59-8 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Ethanol: 66 mg/mL (132.12 mM), Heating is recommended.
DMSO: >10 mM
You can also refer to dose conversion for different animals. More
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
PFI-2 1627676-59-8 Chromatin/Epigenetic Histone Methyltransferase PFI2 Inhibitor inhibit macrophage chronic kidney disease PFI 2 renal fibrosis inflammation (R)-PFI-2 SET domain containing lysine methyltransferase 7 (SETD7) inhibitor