Powder: -20°C for 3 years | In solvent: -80°C for 1 year
PF-9363 (CTX-3648) is a potent and high selective KAT6A/KAT6B inhibitor. PF-9363 can be used for the research of cancer.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 67.00 | |
5 mg | In stock | $ 163.00 | |
10 mg | In stock | $ 263.00 | |
25 mg | In stock | $ 417.00 | |
50 mg | In stock | $ 555.00 | |
100 mg | In stock | $ 773.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 178.00 |
Description | PF-9363 (CTX-3648) is a potent and high selective KAT6A/KAT6B inhibitor. PF-9363 can be used for the research of cancer. |
In vitro | PF-9363 (0~1 μM; 1 day) down-regulates the expression of H3K23Ac biomarker in ZR75-1, T47D and MCF7 cells[1]. PF-9363 downregulates a specific set of genes involved in ESR1 pathway, cell cycle and stem cell pathways. The IC50 values of PF-9363 for ZR75-1 and T47D are 0.3 nM and 0.9 nM[1]. |
In vivo | PF-9363 exihibits strong anti-tumor activity in patient-derived xenograft models[1]. |
Synonyms | CTX-3648 |
Molecular Weight | 444.46 |
Formula | C20H20N4O6S |
CAS No. | 2569009-58-9 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 55 mg/ml (123.75 mM)
You can also refer to dose conversion for different animals. More
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PF-9363 2569009-58-9 Chromatin/Epigenetic Histone Acetyltransferase CTx-648 cancer PF9363 patient-derived anti-tumor HAT CTx648 Inhibitor HATs selective xenograft CTx 648 inhibit PF 9363 CTX3648 CTX-3648 potent CTX 3648 inhibitor