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TargetMol | Compound Library

Histone Modification Compound Library

Catalog No. L3500

A histone modification is a covalent post-translational enzymatic modification to histone proteins which includes methylation, phosphorylation, acetylation, ubiquitylation, and sumoylation. Histone modification impacts gene expression by altering chromatin structure or recruiting histone modifiers. Therefore, histone modifications act in diverse biological processes such as transcriptional activation/inactivation, chromosome packaging, and DNA damage/repair. Thus, quantitative detection of various histone modifications would provide useful information for a better understanding of epigenetic regulation of cellular processes and the development of histone modifying enzyme-targeted drugs.

The TargetMol's Histone Modification Compound Library, a unique collection of 569 histone modification related compounds, can be used for research in histone modification and related drug screening.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.

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Catalog No. L3500

Histone Modification Compound Library

sizeIn stock

  • 1 mg
  • 30 μL x 10 mM (in DMSO)
  • 50 μL x 10 mM (in DMSO)
  • 100 μL x 10 mM (in DMSO)
  • 250 μL x 10 mM (in DMSO)
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Product Description Product Description

  • A unique collection of 569 histone modification related compounds for high throughput screening (HTS) and high content screening (HCS);
  • Detailed compound information with structure, target, activity, IC50 value, and biological activity description;
  • Structurally diverse, medicinally active, and cell permeable;
  • NMR and HPLC validated to ensure high purity and quality;

Packaging And Storage Packaging And Storage

  • Powder or pre-dissolved DMSO solutions in 96/384 well plate with optional 2D barcode
  • Shipped with blue ice
  • This compound library is provided at a concentration of 10 mM in DMSO. A small number of compounds may be provided in different solvents or concentrations due to solubility or stability requirements. Please refer to the specific product information for details.

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Epigenetic Reader Domain
Histone Methyltransferase
HDAC
Apoptosis
Sirtuin
Histone Demethylase
Histone Acetyltransferase
Autophagy
PROTACs
HIV Protease
Endogenous Metabolite
Antibacterial
Mitophagy
Virus Protease
CDK
MDM-2/p53
Ligands for Target Protein for PROTAC
JAK
Parasite
COX
DNA/RNA Synthesis
Monoamine Oxidase
PI3K
Wnt/beta-catenin
PDE
Antiviral
NF-κB
TNF
Dehydrogenase
Antifungal
Adenosine Receptor
Histamine Receptor
Phosphatase
c-Myc
ERK
MAO
Gamma-secretase
Interleukin
EGFR
Influenza Virus
Carboxypeptidase
GABA Receptor
DNA Methyltransferase
PD-1/PD-L1
Dopamine Receptor
RAAS
Tyrosine Kinases
PPAR
PARP
Caspase
NR4A
HSV
MMP
Androgen Receptor
mTOR
OXPHOS
TLR
SARS-CoV
Bcl-2 Family
Nrf2
AMPK
Tyrosinase
p53
Mdm2
DNA-PK
MyD88
Amino Acids and Derivatives
Ferroptosis
Antioxidant
NADPH
PKA
HBV
Serine Protease
Antifolate
PKC
Adrenergic Receptor
IDO
Immunology/Inflammation related
Topoisomerase
UGT
Bcr-Abl
Mitochondrial Metabolism
Glucosidase
Molecular Glues
Reactive Oxygen Species
Fatty Acid Synthase
CCR
Angiotensin-converting Enzyme (ACE)
PAD
Lipoxygenase
Cytochromes P450
Indoleamine 2,3-Dioxygenase (IDO)
Telomerase
Akt
PSMA
HSP
Aminopeptidase
transporter
Methionine Adenosyltransferase (MAT)
IκB/IKK
Beta Amyloid
Reverse Transcriptase
STAT
Phospholipase
5-HT Receptor
PLK
MEK
AChR
FLT
BMI-1
Sodium Channel
NOD
Antibiotic
HIF/HIF Prolyl-Hydroxylase
HER

Keywords