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PDM11

Name: PDM11
Brand: TargetMol
SKU: T5541
Price: 35 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T5541Cas No. 1032508-03-4

Alias PDM 11, 1-[2-(4-Chloro-phenyl)-vinyl]-3,5-diMeth

PDM11 (1-[2-(4-Chloro-phenyl)-vinyl]-3,5-diMeth) is an antagonist of aryl hydrocarbon receptor (AhR)

PDM11

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Purity: 99.88%

Catalog No. T5541Alias PDM 11, 1-[2-(4-Chloro-phenyl)-vinyl]-3,5-diMethCas No. 1032508-03-4

PDM11 (1-[2-(4-Chloro-phenyl)-vinyl]-3,5-diMeth) is an antagonist of aryl hydrocarbon receptor (AhR)

Pack Size	Price	Availability
10 mg	$35	In Stock
25 mg	$73	In Stock
50 mg	$118	In Stock
100 mg	$189	In Stock
200 mg	$278	In Stock
1 mL x 10 mM (in DMSO)	$39	In Stock

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Batch Information

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Purity:99.88%

Resource Download

COA LCMS HNMR

Product Introduction

Bioactivity

Description	PDM11 (1-[2-(4-Chloro-phenyl)-vinyl]-3,5-diMeth) is an antagonist of aryl hydrocarbon receptor (AhR)
Targets&IC50	BRD4(1):77 nM , BRD4(2):33 nM
Synonyms	PDM 11, 1-[2-(4-Chloro-phenyl)-vinyl]-3,5-diMeth

Chemical Properties

Molecular Weight	274.74
Formula	C₁₆H₁₅ClO₂
Cas No.	1032508-03-4
Smiles	C(=C/C1=CC=C(Cl)C=C1)\C2=CC(OC)=CC(OC)=C2
Relative Density.	1.181 g/cm3 (Predicted)

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 10 mg/mL (36.4 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.6398 mL	18.1990 mL	36.3980 mL	181.9902 mL
5 mM	0.7280 mL	3.6398 mL	7.2796 mL	36.3980 mL
10 mM	0.3640 mL	1.8199 mL	3.6398 mL	18.1990 mL
20 mM	0.1820 mL	0.9100 mL	1.8199 mL	9.0995 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc