Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Obefazimod (ABX-464) is a potent anti-HIV agent. ABX464 inhibits HIV-1 replication in stimulated peripheral blood mononuclear cells (PBMCs) (IC50 : 0.1 μM - 0.5 μM)
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 38.00 | |
5 mg | In stock | $ 93.00 | |
10 mg | In stock | $ 148.00 | |
25 mg | In stock | $ 328.00 | |
50 mg | In stock | $ 528.00 | |
100 mg | In stock | $ 769.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 98.00 |
Description | Obefazimod (ABX-464) is a potent anti-HIV agent. ABX464 inhibits HIV-1 replication in stimulated peripheral blood mononuclear cells (PBMCs) (IC50 : 0.1 μM - 0.5 μM) |
Targets&IC50 | HIV-1:0.1 μM - 0.5 μM |
In vivo | ABX464 represents a novel class of anti-HIV molecules with unique properties. ABX464 has a long lasting effect in humanized mice and neutralizes the expression of HIV-1 proviral genome of infected immune cells including reservoirs and it is therefore a promising drug toward a functional cure of HIV[1]. |
Synonyms | ABX-464, ABX464 |
Molecular Weight | 338.71 |
Formula | C16H10ClF3N2O |
CAS No. | 1258453-75-6 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 100 mg/mL (295.24 mM)
You can also refer to dose conversion for different animals. More
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
Obefazimod 1258453-75-6 Microbiology/Virology Proteases/Proteasome HIV Protease ABX 464 HIV ABX-464 Inhibitor Human immunodeficiency virus inhibit ABX464 inhibitor