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NGP555

Catalog No. T16294 CAS 1304630-27-0

NGP555 is a modulator of γ-secretase.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.

NGP555, CAS 1304630-27-0

Pack Size	Availability	Price/USD
2 mg	In stock	101.00
5 mg	In stock	204.00
10 mg	In stock	308.00
25 mg	In stock	636.00
50 mg	In stock	1150.00
100 mg	In stock	1850.00
200 mg	In stock	2775.00
1 mL * 10 mM (in DMSO)	In stock	215.00

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Purity 99.77%

HNMR HPLC COA

Datasheet SDS

Biological Description

Chemical Properties

Storage & Solubility Information

Description	NGP555 is a modulator of γ-secretase.
Targets&IC50	γ-secretase

Molecular Weight	406.52
Formula	C23H23FN4S
CAS No.	1304630-27-0

Storage

Powder: -20°C for 3 years

In solvent: -80°C for 6 months

Solubility Information

DMSO: 25 mg/mL (61.50 mM), Need ultrasonic

( < 1 mg/ml refers to the product slightly soluble or insoluble )

Citations

References and Literature

1. Kounnas MZ, et al. NGP 555, a γ-Secretase Modulator, Lowers the Amyloid Biomarker, Aβ42, in Cerebrospinal Fluid while Preventing Alzheimer's Disease Cognitive Decline in Rodents. Alzheimers Dement (N Y). 2017 Jan;3(1):65-73.

Related compound libraries

This product is contained In the following compound libraries：

Bioactive Compound Library

Related Products

Related compounds with same targets

MDR-1339 Jagged-1 （188-204） Jagged-1 (188-204) TFA(219127-21-6 free base) Fosciclopirox LY900009 PF03084014 L-685,458 IMR1

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

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What is the mass of compound required to make a 10 mM stock solution in 10 ml of water given that the molecular weight of the compound is 197.13 g/mol?
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.