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N-Caffeoyltryptophan

N-Caffeoyltryptophan
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N-Caffeoyltryptophan

Catalog No. TN7093Cas No. 109163-69-1
N-Caffeoyltryptophan (trans-Caffeoyl-L-tryptophan), a potential Sirt inhibitor, is screened using coffee extract. N-Caffeoyltryptophan inhibited Sirt2 (IC50; 8.7 μM) better than Sirt1(IC50; 34μM).
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Pack SizePrice/USDAvailabilityQuantity
1 mg$106In Stock
2 mg$148In Stock
5 mg$239In Stock
10 mg$355In Stock
25 mg$588In Stock
50 mg$838In Stock
1 mL x 10 Mm (in DMSO)$259In Stock
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Related Compound Libraries of "N-Caffeoyltryptophan"

Product Introduction

Bioactivity
Description
N-Caffeoyltryptophan (trans-Caffeoyl-L-tryptophan), a potential Sirt inhibitor, is screened using coffee extract. N-Caffeoyltryptophan inhibited Sirt2 (IC50; 8.7 μM) better than Sirt1(IC50; 34μM).
In vitro
In cellular levels,N-Caffeoyltryptophan was able to increase the acetylation of total lysine, cortactin and histone H3 in neuronal NG108-15 cells. In the same cells, the amide also increased the acetylation of lysine (K382) in p53, but not (K305)[1].
Aliastrans-Caffeoyl-L-tryptophan
Chemical Properties
Molecular Weight366.37
FormulaC20H18N2O5
Cas No.109163-69-1
Storage & Solubility Information
Storagekeep away from moisture Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Solubility Information
DMSO: 45 mg/mL (122.83 mM)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.7295 mL13.6474 mL27.2948 mL136.4741 mL
5 mM0.5459 mL2.7295 mL5.4590 mL27.2948 mL
10 mM0.2729 mL1.3647 mL2.7295 mL13.6474 mL
20 mM0.1365 mL0.6824 mL1.3647 mL6.8237 mL
50 mM0.0546 mL0.2729 mL0.5459 mL2.7295 mL
100 mM0.0273 mL0.1365 mL0.2729 mL1.3647 mL

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