Powder: -20°C for 3 years
In solvent: -80°C for 2 years
Moracin C and D, new phytoalexins from diseased mulberry, are antifungal compounds.
Description | Moracin C and D, new phytoalexins from diseased mulberry, are antifungal compounds. |
In vitro | In the screening of inhibitors of Staphylococcus aureus enoyl-ACP reductase (FabI), we found that a methanol extract of leaves of Morus alba L. potently inhibited S. aureus FabI as well as growth of S. aureus. The active principles were identified as chalcomoracin and Moracin C by MS and NMR analysis. Chalcomoracin and Moracin C inhibited S. aureus FabI with IC(50) of 5.5 and 83.8 μM, respectively. They also prevented the growth of S. aureus with minimum inhibitory concentration (MIC) of 4 and 32 μg/mL, respectively. Consistent with their inhibition against FabI and bacterial growth, they prevented (14)C]acetate incorporation into fatty acid in S. aureus while didn't affect protein synthesis. |
Synonyms | 5-(6-羟基-2-苯并呋喃基)-2-(3-甲基-2-丁烯基)-1,3-苯二醇, 桑辛素 C |
Molecular Weight | 310.34 |
Formula | C19H18O4 |
CAS No. | 69120-06-5 |
Powder: -20°C for 3 years
In solvent: -80°C for 2 years
( < 1 mg/ml refers to the product slightly soluble or insoluble )
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Moracin C 69120-06-5 免疫与炎症 神经科学 NOS COX ROS Inhibitor inhibitor inhibit