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Lup-20(29)-en-28-oic acid

Catalog No. TN2118 CAS 848784-85-0

Synonyms: 白头翁皂苷D, Pulsatilla saponin D

Lup-20(29)-en-28-oic acid exhibits anticancer activities in various cancer types, it Inhibits autophagic flux and synergistically enhances the anticancer activity of chemotherapeutic agents against HeLa cells.Pulsatilla saponin D has strong haemolytic activity.

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Lup-20(29)-en-28-oic acid, CAS 848784-85-0

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Purity: 98%

Biological Description

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Description	Lup-20(29)-en-28-oic acid exhibits anticancer activities in various cancer types, it Inhibits autophagic flux and synergistically enhances the anticancer activity of chemotherapeutic agents against HeLa cells.Pulsatilla saponin D has strong haemolytic activity.
In vitro	The strong hemolytic toxicity of Pulsatilla saponin D (1, HD50 6.3 μM) has hampered its clinical development as an injectable anticancer agent.

Synonyms	白头翁皂苷D, Pulsatilla saponin D
Molecular Weight	913.1
Formula	C47H76O17
CAS No.	848784-85-0

Storage

Powder: -20°C for 3 years

In solvent: -80°C for 2 years

Solubility Information

( < 1 mg/ml refers to the product slightly soluble or insoluble )

References and Literature

1. Cytotoxicity, Hemolytic Toxicity, and Mechanism of Action of Pulsatilla Saponin D and Its Synthetic Derivatives.J Nat Prod. 2018 Mar 23;81(3):465-474.

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Hirsutenone Flavoglaucin Lup-20(29)-en-28-oic acid Onjisaponin B PTC-209 hydrobromide PF-543 Brivanib LYN-1604

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Keywords

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