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Substance P(1-7)
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Catalog No. T7396Cas No. 68060-49-1
Alias Substance P 1-7
Substance P(1-7) (Substance P 1-7) is the major bioactive metabolite formed after proteolytic degradation of the tachykinin substance P (SP),with anti-inflammatory, anti-nociceptive and anti-hyperalgesic effects
Substance P(1-7)
😃Good
Catalog No. T7396Alias Substance P 1-7Cas No. 68060-49-1
Substance P(1-7) (Substance P 1-7) is the major bioactive metabolite formed after proteolytic degradation of the tachykinin substance P (SP),with anti-inflammatory, anti-nociceptive and anti-hyperalgesic effects
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 2 mg | $70 | Backorder | |
| 5 mg | $98 | Backorder | |
| 10 mg | $160 | Backorder | |
| 25 mg | $288 | Backorder | |
| 50 mg | $432 | Backorder | |
| 100 mg | $648 | Backorder |
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Product Introduction
Bioactivity
Chemical Properties
| Description | Substance P(1-7) (Substance P 1-7) is the major bioactive metabolite formed after proteolytic degradation of the tachykinin substance P (SP),with anti-inflammatory, anti-nociceptive and anti-hyperalgesic effects |
| In vivo | Substance P 1-7, SP(1-7), which is the main SP fragment in rat CNS, was injected intranigrally. SP(1-7) was found to act as a very potent antagonist against the SP-induced responses and was formed locally in the nigra after SP injection. It is proposed that SP(1-7) is an endogenous modulator of SP actions. Generation of peptide fragments, which retain receptor affinity but not efficacy, may be a general mechanism for autoregulation in peptidergic systems[1]. |
| Alias | Substance P 1-7 |
| Molecular Weight | 900.04 |
| Formula | C41H65N13O10 |
| Cas No. | 68060-49-1 |
| Relative Density. | 1.49 g/cm3 (Predicted) |
Storage & Solubility Information
| Storage | keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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