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Eledoisin Related Peptide

Catalog No. T7631 CAS 2990-43-4

Synonyms: Eledoisin Related Peptide(2TFA), Eledoisin-Related Peptide, Eledoisin RP

Eledoisin Related Peptide(2TFA) is a tachykinin receptor ligand.

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Eledoisin Related Peptide, CAS 2990-43-4

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Purity: 98%

Biological Description

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Description

Eledoisin Related Peptide(2TFA) is a tachykinin receptor ligand.

In vivo

Substance P and eledoisin-related peptide had excitatory effects on respiratory neurones and reflex interneurones, but compared with glutamate-induced effects the excitation was slower in onset and more prolonged in after-discharge.?Both rhythmic and evoked activity could be facilitated, and the magnitude of the effect varied directly with the magnitude of the ejecting current.?In showing that both glutamate and substance P (and its analogue, eledoisin-related peptide) have excitatory effects on the activity of respiratory neurones and reflex interneurones[1].

Synonyms	Eledoisin Related Peptide(2TFA), Eledoisin-Related Peptide, Eledoisin RP
Molecular Weight	706.94
Formula	C34H58N8O6S
CAS No.	2990-43-4

Storage

Powder: -20°C for 3 years

In solvent: -80°C for 2 years

Solubility Information

DMSO: 10 mM

( < 1 mg/ml refers to the product slightly soluble or insoluble )

References and Literature

1. Severini C, et al. The tachykinin peptide family. Pharmacol Rev. 2002 Jun;54(2):285-322. 1. Henry J L , Sessle B J . Effects of glutamate, substance P and eledoisin-related peptide on solitary tract neurones involved in respiration and respiratory reflexes[J]. Neuroscience, 1985, 14(3):863-873. 2. Guyenet P G , Aghajanian G K . Excitation of neurons in the nucleus locus coeruleus by substance P and related peptides[J]. Brain Research, 1977, 136(1):178-184.

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