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TargetMol | Compound Library

Multi-Target Compound Library

Catalog No. L9510

The pathogenesis of complex diseases often involves the interplay of multiple biological targets and signaling pathways, making it difficult for single-target drugs to achieve optimal therapeutic outcomes. As a result, single-target treatment strategies may have limited efficacy in certain cases. In contrast, multi-target drugs can act on multiple key targets or related pathways simultaneously, producing synergistic effects that significantly enhance therapeutic effectiveness.
This integrated intervention approach not only facilitates more comprehensive regulation of disease-associated biological networks but also helps to reduce the risk of drug resistance caused by mutations in individual targets. Moreover, due to the synergistic interactions between different targets, multi-target drugs can achieve desired therapeutic outcomes at lower dosages, thereby reducing toxicity and improving both safety and tolerability.
Therefore, multi-target drugs offer a more systematic and efficient strategy for the treatment of complex diseases.
TargetMol’s Multi-Target Compound Library contains 5200 compounds that act on two or more distinct targets, providing a valuable resource for the development of multi-target therapeutics.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.

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Catalog No. L9510

Multi-Target Compound Library

sizeIn stock

  • 1 mg
  • 30 μL x 10 mM (in DMSO)
  • 50 μL x 10 mM (in DMSO)
  • 100 μL x 10 mM (in DMSO)
  • 250 μL x 10 mM (in DMSO)
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Product Description Product Description

  • A unique collection of 5200 types of multi-target compounds for high throughput screening (HTS) and high content screening (HCS);
  • Approved by FDA and already on the market;
  • Structurally diverse, medicin active, and cell-permeable.
  • More detailed compound information with structure, target, activity, IC50 value, and brief introduction;
  • NMR and HPLC validated to ensure high purity and quality;
  • All compounds are available in stock for immediate delivery.

Packaging And Storage Packaging And Storage

  • Powder or pre-dissolved DMSO solutions in 96/384 well plate with optional 2D barcode
  • Shipped with blue ice
  • This compound library is provided at a concentration of 10 mM in DMSO. A small number of compounds may be provided in different solvents or concentrations due to solubility or stability requirements. Please refer to the specific product information for details.

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Library Customization | TargetMol Library Composition

Apoptosis
Autophagy
Endogenous Metabolite
5-HT Receptor
Antibacterial
NF-κB
ROS
CDK
PI3K
COX
Dopamine Receptor
Adrenergic Receptor
DNA/RNA Synthesis
Potassium Channel
AChR
EGFR
VEGFR
HIV Protease
Akt
Cytochromes P450
Reactive Oxygen Species
Calcium Channel
ERK
Antibiotic
p38 MAPK
TNF
Parasite
Ras
Caspase
Histamine Receptor
mTOR
Epigenetic Reader Domain
PPAR
Sodium Channel
JAK
Interleukin
Src
NO Synthase
Virus Protease
FLT
Estrogen/progestogen Receptor
PDGFR
Ferroptosis
iGluR
PDE
Dehydrogenase
STAT
Bcl-2 Family
SARS-CoV
FGFR
HDAC
Influenza Virus
IL Receptor
Wnt/beta-catenin
PKC
Histone Methyltransferase
Estrogen Receptor/ERR
TRP/TRPV Channel
c-Kit
PARP
GSK-3
JNK
AMPK
GABA Receptor
Antifungal
MMP
Microtubule Associated
Prostaglandin Receptor
NMDAR
c-Met/HGFR
Bcr-Abl
MDM-2/p53
TLR
Cholinesterase (ChE)
GluR
Raf
ALK
HSV
MAPK
Phosphatase
Monoamine Oxidase
MAO
Mitophagy
TGF-beta/Smad
Beta Amyloid
Tyrosine Kinases
HIF/HIF Prolyl-Hydroxylase
Aurora Kinase
Topoisomerase
Drug Metabolite
Proteasome
HSP
HCV Protease
MEK
GPCR
Nrf2
PKA
Casein Kinase
Lipoxygenase
P-gp
Norepinephrine
Cannabinoid Receptor
Reverse Transcriptase
p53
Serotonin Transporter
ATPase
E1/E2/E3 Enzyme
Sirtuin
Adenosine Receptor
IκB/IKK
Mitochondrial Metabolism
ROCK
IGF-1R
S6 Kinase
LPL Receptor
NOS
RAAS
Phospholipase
Antiviral
TAM Receptor
Anti-infection
Serine Protease
Glucocorticoid Receptor
HBV
Gamma-secretase
Serine/threonin kinase
DNA-PK
Opioid Receptor
Retinoid Receptor
S1P Receptor
HIF
c-RET
NOD-like Receptor (NLR)
Carbonic Anhydrase
PERK
Nucleoside Antimetabolite/Analog
HER
Trk receptor
Integrin
Antioxidant
DUB
Androgen Receptor
Cysteine Protease
Tyrosinase
FAK
Histone Acetyltransferase
CaMK
c-Fms
Histone Demethylase
Progesterone Receptor
Pim
PROTACs
Mdm2
CXCR
Transferase
HMG-CoA Reductase
DYRK
NOD
DNA Alkylator/Crosslinker
Hedgehog/Smoothened
ATM/ATR
CCR
Rho
ROS Kinase
Glutathione Peroxidase
Reductase
Glucosidase
transporter
RIP kinase
Angiotensin-converting Enzyme (ACE)
Syk
Aryl Hydrocarbon Receptor
Beta-Secretase
BACE
NADPH
DNA Methyltransferase
MRP
Sigma receptor
Immunology/Inflammation related
Chk
PLK
KRas
Antifection
Fatty Acid Synthase
DPP-4
Proton pump
Smo
IDO
P2X Receptor
Indoleamine 2,3-Dioxygenase (IDO)
Chloride channel
Acyltransferase
AhR
FAAH
c-Myc
PAK
Leukotriene Receptor
DNA Alkylation
glycosidase
DNA
CSF-1R
Stearoyl-CoA Desaturase (SCD)
SGLT
PDK
Kinesin
IAP
GPCR19
Isocitrate Dehydrogenase (IDH)
cAMP
FXR
LDL
ADC Cytotoxin
YAP
Thrombin
LTR
ABC Transporter
Liver X Receptor
IRAK
Melatonin Receptor
PGE Synthase
P2Y Receptor
PTEN
Pyroptosis
Tie-2
IFNAR
Telomerase
Lipid
LPA Receptor
UGT
Discoidin Domain Receptor (DDR)
Amino Acids and Derivatives
MNK
PD-1/PD-L1
OXPHOS
LRRK2
DHFR
Myosin
Endothelin Receptor
Necroptosis
MT Receptor
Molecular Glues
OX Receptor
BCRP
CFTR
PI4K
BTK
DNA gyrase
Xanthine Oxidase
Epoxide Hydrolase
MLK
Antifolate
PYK2
Monoamine Transporter
ribosome
Lipase
LIM Kinase
GTPase
Aromatase
STING
Free radical scavengers
NADPH-oxidase
Thyroid hormone receptor(THR)
Annexin A
SGK
Aminopeptidase
MicroRNA
ROR
Ligands for Target Protein for PROTAC
PAFR
RSV
Vasopressin Receptor
Ephrin Receptor
GST
Guanylate cyclase
FKBP
SIK
Neurokinin receptor
Survivin
CRISPR/Cas9
Hydroxylase
Glucagon Receptor
Complement System
Arginase
PAI-1
Platelet aggregation
IKZF
RAR/RXR
MyD88
Arrestin
IRE1
MAGL
Cadherin
GPX
Phosphorylase
ASK
Protease-activated Receptor
ATP Citrate Lyase
Imidazoline Receptor
Glucokinase
OAT
Factor Xa
NAMPT
NPC1L1
AAK1
Decarboxylase
FOXO
Bcl-6
ACK1
Glutaminase
NR4A
Porcupine
cGAS
Dynamin
MTH1
Na+/Ca2+ Exchanger
AIM2
Carboxypeptidase
Amylase
GluCls
CGRP Receptor
Melanin-concentrating Hormone Receptor (MCHR)
TOPK
Cholecystokinin Receptor
Ligand for E3 Ligase
Adenosine Deaminase
OCT
Hck
RANKL/RANK
GRK
Bombesin Receptor
Adenylyl Cyclase
Transaminase
GlyT
PAD
Thrombopoietin Receptor
Wee1
Methionine Adenosyltransferase (MAT)
Aquaporin
Cuproptosis
NEDD8
ATG
Hexokinase
Orphan Receptor
CRFR
Melanocortin Receptor
GHSR
Gap Junction Protein
FOXO3
Monocarboxylate transporter
FABP
KSP
Huntingtin
PKM
LDLR
FLAP
Neuropeptide FF Receptor
Glutathione reductase
Neprilysin
Advanced Glycation End Products
AAK1 (AP2 associated kinase 1)
Arp2/3 Complex
Na-K-Cl cotransporter
BMI-1
CRM1
MIF
DAPK
VDA
Adiponectin Receptor
Hippo pathway
p62
Cell Cycle Arrest
Haspin Kinase
Protease
KLF
gp120/CD4
GNRH Receptor
ASCT
CPT
MELK
Oxytocin Receptor
REV-ERB
Lysosomal Autophagy
Prolyl Endopeptidase (PREP)
Acetyl-CoA Carboxylase
RXFP receptor
ATTECs
Taste receptor
Aconitase
Integrase
APC/C
Cell wall
CETP
Fas/FasL
Neuropeptide Y Receptor
hCE
Somatostatin
Urea Transporter
p97
N-Acetylglucosaminyltransferase
Anion Exchanger
PROTAC Linker
CD74
Tight Junction Protein
CAT
GSNOR
EBI2/GPR183
Y Box Binding Protein 1
CaSR
Photosensitizer
HCN Channel

Keywords