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GSA-10

Catalog No. T22814 CAS 300833-95-8

GSA-10 is a potent Smoothened (Smo) receptor agonist with an EC50 of 1.2 μM. It acts on Smo to promote the differentiation of pluripotent mesenchymal stem cells into osteoblasts. It also mediates Hedgehog (Hh) signaling, which may have research implications for regenerative medicine in cancer diseases.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.

GSA-10, CAS 300833-95-8

Pack Size	Availability	Price/USD
1 mg	In stock	$ 135.00
2 mg	In stock	$ 197.00
5 mg	In stock	$ 313.00
10 mg	In stock	$ 468.00
25 mg	In stock	$ 753.00
50 mg	In stock	$ 987.00
100 mg	In stock	$ 1,390.00

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Biological Description

Chemical Properties

Storage & Solubility Information

Description	GSA-10 is a potent Smoothened (Smo) receptor agonist with an EC50 of 1.2 μM. It acts on Smo to promote the differentiation of pluripotent mesenchymal stem cells into osteoblasts. It also mediates Hedgehog (Hh) signaling, which may have research implications for regenerative medicine in cancer diseases.
Targets&IC50	Smo receptor:1.2 μM(EC50)

Molecular Weight	450.53
Formula	C26H30N2O5
CAS No.	300833-95-8

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: Insoluble

Related compound libraries

This product is contained In the following compound libraries：

Anti-Cancer Active Compound Library GPCR Compound Library Anti-Prostate Cancer Compound Library Neuronal Differentiation Compound Library Bioactive Compound Library Stem Cell Differentiation Compound Library Bioactive Compounds Library Max Anti-Cancer Compound Library

Related Products

Related compounds with same targets

MRT-10 BMS-833923 RU-SKI 43 Naftifine hydrochloride Sonidegib CUR61414 hydrochloride Tolnaftate SMO-IN-2

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

GSA-10 300833-95-8 GPCR/G Protein Stem Cells Hedgehog/Smoothened Inhibitor differentiation regenerative medicine Smoothened receptor quinolinecarboxamide derivative GSA 10 cancer Smoothened GSA10 Smo osteoblasts Hedgehog inhibit multipotent mesenchymal progenitor cell inhibitor

Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.