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Evodine

Catalog No. TCS2336 CAS 6989-38-4

1. Evodine has antinociceptive activity.

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Evodine, CAS 6989-38-4

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Purity: 98%

Biological Description

Chemical Properties

Storage & Solubility Information

Description

1. Evodine has antinociceptive activity.

Molecular Weight	329.352
Formula	C18H19NO5
CAS No.	6989-38-4

Storage

Powder: -20°C for 3 years

In solvent: -80°C for 2 years

Solubility Information

DMSO: 60 mg/mL(182.2 mM)

Chloroform, Dichloromethane, Ethyl Acetate, Acetone, etc.: Soluble

( < 1 mg/ml refers to the product slightly soluble or insoluble )

References and Literature

1. Cai Q Y , Li W R , Wei J J , et al. Antinociceptive activity of aqueous and alcohol extract of evodia rutaecarpa.[J]. Indian Journal of Pharmaceutical Sciences, 2014, 76(3):235-239.

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Dose Conversion

You can also refer to dose conversion for different animals. More

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Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

Note:

Be sure to add the solvent(s) in order. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.

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An example of a molarity calculation using the molarity calculator
What is the mass of compound required to make a 10 mM stock solution in 10 ml of water given that the molecular weight of the compound is 197.13 g/mol?
Enter 197.13 into the Molecular Weight (MW) box
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The answer of 19.713 mg appears in the Mass box

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The dilution calculator is a useful tool which allows you to calculate how to dilute a stock solution of known concentration. Enter C1, C2 & V2 to calculate V1.

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An example of a dilution calculation using the Tocris dilution calculator
What volume of a given 10 mM stock solution is required to make 20ml of a 50 μM solution?
Using the equation C1V1 = C2V2, where C1=10 mM, C2=50 μM, V2=20 ml and V1 is the unknown:
Enter 10 into the Concentration (start) box and select the correct unit (millimolar)
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The answer of 100 microliter (0.1 ml) appears in the Volume (start) box

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Molar mass (molar weight) is the mass of one mole of a substance and is expressed in g/mol.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

Evodine 6989-38-4 离子通道神经科学 P-gp Inhibitor ABCB1 Pgp MDR1 Cluster of differentiation 243 Multidrug resistance protein 1 P-glycoprotein CD243 inhibit inhibitor

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