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Ethyl glucoside

Catalog No. TN2401 CAS 3198-49-0

Synonyms: β-D-Glucopyranoside, ethyl, Ethyl D-glucoside

Ethyl glucoside (β-D-Glucopyranoside, ethyl), a shale inhibitor for water-based drilling fluids, is a versatile initiator of enzyme-catalyzed regioselective lactone ring-opening polymerization and is a natural compound found in Sisyrinchium palmifolium.

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Ethyl glucoside, CAS 3198-49-0

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Purity: 99.68%

Biological Description

Chemical Properties

Storage & Solubility Information

Description	Ethyl glucoside (β-D-Glucopyranoside, ethyl), a shale inhibitor for water-based drilling fluids, is a versatile initiator of enzyme-catalyzed regioselective lactone ring-opening polymerization and is a natural compound found in Sisyrinchium palmifolium.
In vitro	EG exists as alpha (α) and beta (β) isomers. In this study, 0.48 μM of α-EG was found to increase the proliferation of normal human dermal fibroblasts (NHDF) by 121.0%, and the amount of collagen I produced by NHDF increased by 159.6% at an α-EG concentration of 0.048 μM, compared to those in cells cultured without α-EG. In NHDF cultured in α-EG-supplemented medium, the expression of fibroblast growth factor I and VII mRNA increased by 148.8 and 153.1%, at an α-EG concentration of 4.8 and 0.048 μM, respectively, as measured by a quantitative reverse transcription-polymerase chain reaction. Transcript levels of type I collagen genes, COL1A1 and COL1A2, increased by 152.4 and 129.7%, respectively, and that of a type III collagen gene, COL3A1, increased by 131.8% at an α-EG concentration of 0.48 μM.[3][4]
In vivo	Metabonomic screening of human urine samples using 1H NMR spectroscopy has revealed the presence of signals resulting from the excretion of Ethyl glucoside. Experiments in volunteers have demonstrated that this Ethyl glucoside results from dietary exposure to the compound, which is present in beverages such as rice wine and sake, rather than representing a new route for the metabolism of ethanol by humans. The limited studies undertaken in volunteers indicate that Ethyl glucoside has a longer biological half life than ethanol itself. The potential problems associated with using this glucoside metabolite as a marker of ethanol consumption are considered.[2]

Synonyms	β-D-Glucopyranoside, ethyl, Ethyl D-glucoside
Molecular Weight	208.21
Formula	C8H16O6
CAS No.	3198-49-0

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 60 mg/mL (288.17 mM)

References and Literature

1. Bisht K S , et al. Ethyl Glucoside as a Multifunctional Initiator for Enzyme-Catalyzed Regioselective Lactone Ring-Opening Polymerization. Journal of the American Chemical Society, 1998;120(7):1363-1367. 2. Teague C , et al. Ethyl glucoside in human urine following dietary exposure: detection by 1H NMR spectroscopy as a result of metabonomic screening of humans. Analyst, 2004;129(3):259. 3. Waters B, et al. A validated method for the separation of ethyl glucoside isomers by gas chromatography-tandem mass spectrometry and quantitation in human whole blood and urine. J Chromatogr B Analyt Technol Biomed Life Sci. 2022;1188:123074. 4. Bogaki T, et al. Effects of ethyl-α-d-glucoside on human dermal fibroblasts. Biosci Biotechnol Biochem. 2017;81(9):1706-1711.

Related compound libraries

This product is contained In the following compound libraries：

Natural Product Library for HTS Natural Product Library Traditional Chinese Medicine Monomer Library Bioactive Compound Library Saccharide and Glycoside Natural Product Library Selected Plant-Sourced Compound Library Bioactive Compounds Library Max

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Keywords

Ethyl glucoside 3198-49-0 Others b-D-Glucopyranoside, ethyl β-D-Glucopyranoside, ethyl Ethyl D-glucoside beta-D-Glucopyranoside, ethyl inhibitor inhibit

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