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DuP 105

Catalog No. T11123 CAS 96800-41-8

DuP 105 is an oral oxazolidinone, a novel synthetic antimicrobial compound effective against gram-positive bacteria.

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DuP 105, CAS 96800-41-8

Pack Size	Availability	Price/USD
1 mg	In stock	$ 995.00
5 mg	In stock	$ 1,990.00
10 mg	In stock	$ 2,680.00
25 mg	In stock	$ 3,980.00
50 mg	In stock	$ 5,380.00
100 mg	In stock	$ 7,260.00
1 mL * 10 mM (in DMSO)	In stock	$ 1,990.00

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Purity: 100%

Biological Description

Chemical Properties

Storage & Solubility Information

Description	DuP 105 is an oral oxazolidinone, a novel synthetic antimicrobial compound effective against gram-positive bacteria.
In vitro	DuP 105 MICs for 50% of the 216 gram-positive isolates tested (MIC50s) range from 4.0 to 16 μg/mL.DuP 105 shows inhibitory activities against staphylococcal isolates and B. fragilis isolates with MIC90s of 4 to 16 μg/mL and 16 μg/mL.
In vivo	Administered orally or parenterally, DuP 105 effectively safeguards mice against staphylococcal and streptococcal infections, displaying 50% efficacy at doses ranging from 9 to 23 mg/kg.

Molecular Weight	296.34
Formula	C13H16N2O4S
CAS No.	96800-41-8

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 45 mg/mL (151.85 mM)

References and Literature

1. Slee AM, et al. Oxazolidinones, a new class of synthetic antibacterial agents: in vitro and in vivo activities of DuP 105 and DuP 721. Antimicrob Agents Chemother. 1987 Nov;31(11):1791-7. 2. Barry AL, et al. In vitro evaluation of DuP 105 and DuP 721, two new oxazolidinone antimicrobial agents. Antimicrob Agents Chemother. 1988 Jan;32(1):150-2.

Related compound libraries

This product is contained In the following compound libraries：

Bioactive Compound Library ReFRAME Related Library Bioactive Compounds Library Max

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Related compounds with same targets

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Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

Note:

Be sure to add the solvent(s) in order. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.

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What is the mass of compound required to make a 10 mM stock solution in 10 ml of water given that the molecular weight of the compound is 197.13 g/mol?
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What volume of a given 10 mM stock solution is required to make 20ml of a 50 μM solution?
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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

DuP 105 96800-41-8 Microbiology/Virology Antibacterial Antibiotic DuP-105 DuP105 inhibitor inhibit

Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.