Powder: -20°C for 3 years | In solvent: -80°C for 1 year
2',3'-Dideoxyadenosine is an inhibitor of HIV replication with antiretroviral activity and antiviral efficacy [1].
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
5 mg | In stock | $ 39.00 | |
10 mg | In stock | $ 64.00 | |
25 mg | In stock | $ 105.00 | |
50 mg | In stock | $ 153.00 | |
100 mg | In stock | $ 229.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 70.00 |
Description | 2',3'-Dideoxyadenosine is an inhibitor of HIV replication with antiretroviral activity and antiviral efficacy [1]. |
In vitro | 2',3'-Dideoxyadenosine effectively inhibits the replication of HIV-1, simian immunodeficiency virus (SIV), and murine sarcoma virus (MSV) across various cell lines. In MT-4 cells, it shows EC50 values of 5.27 μM for HIV-1 and 5.3 μM for SIV. It also inhibits HIV-1 and HIV-2 in human T-lymphocyte CEM cells with EC50 values of 4 μM and 8 μM, respectively, and achieves similar inhibitory effects in Molt 4/C8 and C8166 cells, with EC50 values ranging from 4 μM to 22 μM for both viruses. Furthermore, it demonstrates inhibition against MSV in C3H/3T3 cells with an EC50 of 24 μM. |
Molecular Weight | 235.24 |
Formula | C10H13N5O2 |
CAS No. | 4097-22-7 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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Dideoxyadenosine 4097-22-7 inhibitor inhibit