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Dichlorophen

Catalog No. T0066 CAS 97-23-4

Synonyms: DDM, Dichlorophene

Dichlorophen (DDM) is a nontoxic laxative vermicide of chlorinated phenol compound. Dichlorophen is used as a veterinary fungicide, anthelmintic, and anti-protozoan, as well as an ingredient in antimicrobial soaps and shampoos. This agent probably acts by increasing the clearing of intestinal contents, thereby eradicating tapeworm infections from the intestines.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.

Dichlorophen, CAS 97-23-4

Pack Size	Availability	Price/USD
500 mg	In stock	$ 41.00
1 g	In stock	$ 48.00
1 mL * 10 mM (in DMSO)	In stock	$ 45.00

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Purity: 99.85%

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Description

Kinase Assay

Effect of inhibition of Acetaminophen on COX-1 and COX-2 activity in human whole blood: For COX-1 assay, aliquots of human whole blood drawn from healthy volunteers without anticoagulant are transferred to glass tubes containing Acetaminophen or DMSO, serum is separated by centrifugation after clotting, and serum TxB2 levels are determined. For COX-2 assay, aliquots of heparinized whole blood are incubated with LPS (10 μg/mL) and aspirin (10 μg/mL), plus Acetaminophen or DMSO for 24 hours at 37 °C, plasma is separated by centrifugation, and PGE2 levels are determined subsequently. The degree of COX-1 or COX-2 inhibition is calculated as the percentage change of plasma eicosanoid (TxB2 for COX-1 and PGE2 for COX-2).Concentration response curves are fitted by a sigmoidal regression with variable slope for both enzymatic assays, and the 50% inhibitory concentration (IC50) values are derived by using of PRISM Version 3.0.

Synonyms	DDM, Dichlorophene
Molecular Weight	269.12
Formula	C13H10Cl2O2
CAS No.	97-23-4

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 49 mg/mL(182.1 mM)

References and Literature

1. Langrand J, et al. Clin Toxicol (Phila). 2013 Mar;51(3):178-81.

Related compound libraries

This product is contained In the following compound libraries：

Anti-Parasitic Compound Library Anti-Fungal Compound Library Human Metabolite Library Immunology/Inflammation Compound Library Anti-Bacterial Compound Library Anti-Infection Compound Library Antibiotics Library Bioactive Compounds Library Max NO PAINS Compound Library FDA-Approved & Pharmacopeia Drug Library

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Keywords

Dichlorophen 97-23-4 Microbiology/Virology Antibacterial Parasite Antifungal Fungal Inhibitor Bacterial DDM Dichlorophene inhibit inhibitor

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