Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Dub-in-2, with an IC50 value of 0.28 for USP8, is an effective deubiquitinase inhibitor.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 139.00 | |
2 mg | In stock | $ 196.00 | |
5 mg | In stock | $ 298.00 | |
10 mg | In stock | $ 429.00 | |
25 mg | In stock | $ 696.00 | |
50 mg | In stock | $ 987.00 | |
100 mg | In stock | $ 1,360.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 309.00 |
Description | Dub-in-2, with an IC50 value of 0.28 for USP8, is an effective deubiquitinase inhibitor. |
Targets&IC50 | USP8:0.28 μM |
In vitro | DUBs-IN-2 inhibits the viability of HCT116 colon cell line and PC-3 prostate cancer cell line with IC50 values of 0.5-1.5?μM.DUBs-IN-2 is a potent USP8 inhibitor with an IC50 of 0.28 μM, and has no effect on USP7, with an IC50 of >100 μM. |
Molecular Weight | 275.26 |
Formula | C15H9N5O |
CAS No. | 924296-19-5 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 9.06 mg/mL (32.91 mM), sonification/heating is recommended.
You can also refer to dose conversion for different animals. More
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
DUB-IN-2 924296-19-5 Cell Cycle/Checkpoint DNA Damage/DNA Repair Ubiquitination DUB Inhibitor DUBs inhibit DUBIN2 Deubiquitinase DUB IN 2 inhibitor