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Broussonin E

Catalog No. TN3541 CAS 90902-21-9

Broussonin E could suppress inflammation by modulating macrophages activation STATe via inhibiting the ERK and p38 MAPK and enhancing JAK2-STAT3 signaling pathway, and can be further developed as a promising drug for the treatment of inflammation-related diseases such as atherosclerosis.

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Broussonin E, CAS 90902-21-9

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Purity: 98%

Biological Description

Chemical Properties

Storage & Solubility Information

Description

Broussonin E could suppress inflammation by modulating macrophages activation state via inhibiting the ERK and p38 MAPK and enhancing JAK2-STAT3 signaling pathway, and can be further developed as a promising drug for the treatment of inflammation-related diseases such as atherosclerosis.

Molecular Weight	288.34
Formula	C17H20O4
CAS No.	90902-21-9

Storage

Powder: -20°C for 3 years

In solvent: -80°C for 2 years

Solubility Information

( < 1 mg/ml refers to the product slightly soluble or insoluble )

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

Broussonin E 90902-21-9 Angiogenesis Apoptosis Chromatin/Epigenetic JAK/STAT signaling MAPK Stem Cells TNF p38 MAPK ERK JAK STAT Inhibitor inhibitor inhibit

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