Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Ammonium formate (Formic acid ammonium salt) is the simplest carboxylic acid. Formate is an intermediate in normal metabolism. It is responsible for both metabolic acidosis and disrupting mitochondrial electron transport and energy production by inhibiting cytochrome oxidase activity, the terminal electron acceptor of the electron transport chain. Cell death from cytochrome oxidase inhibition by formate is believed to result partly from depletion of ATP, reducing energy concentrations so that essential cell functions cannot be maintained. Furthermore, inhibition of cytochrome oxidase by formate may also cause cell death by increased production of cytotoxic reactive oxygen species (ROS) secondary to the blockade of the electron transport chain.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
5 mg | In stock | $ 38.00 | |
10 mg | In stock | $ 52.00 | |
25 mg | In stock | $ 81.00 | |
50 mg | In stock | $ 122.00 | |
100 mg | In stock | $ 182.00 | |
200 mg | In stock | $ 273.00 | |
500 mg | In stock | $ 512.00 |
Description | Ammonium formate (Formic acid ammonium salt) is the simplest carboxylic acid. Formate is an intermediate in normal metabolism. It is responsible for both metabolic acidosis and disrupting mitochondrial electron transport and energy production by inhibiting cytochrome oxidase activity, the terminal electron acceptor of the electron transport chain. Cell death from cytochrome oxidase inhibition by formate is believed to result partly from depletion of ATP, reducing energy concentrations so that essential cell functions cannot be maintained. Furthermore, inhibition of cytochrome oxidase by formate may also cause cell death by increased production of cytotoxic reactive oxygen species (ROS) secondary to the blockade of the electron transport chain. |
Synonyms | Formic acid ammonium salt |
Molecular Weight | 63.06 |
Formula | CH5NO2 |
CAS No. | 540-69-2 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 200 mM
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Ammonium formate 540-69-2 Others Formic acid ammonium Ammonium Formate Formic acid ammonium salt inhibitor inhibit