Powder: -20°C for 3 years | In solvent: -80°C for 1 year
AZD3229 is a potent pan-KIT mutant inhibitor for the treatment of gastrointestinal stromal tumors. It demonstrates potent single-digit nM growth inhibition across a broad cell panel.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 62.00 | |
5 mg | In stock | $ 148.00 | |
10 mg | In stock | $ 239.00 | |
25 mg | In stock | $ 433.00 | |
50 mg | In stock | $ 638.00 | |
100 mg | In stock | $ 892.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 167.00 |
Description | AZD3229 is a potent pan-KIT mutant inhibitor for the treatment of gastrointestinal stromal tumors. It demonstrates potent single-digit nM growth inhibition across a broad cell panel. |
In vivo | Following a single dose (AZD3229, 20 mg/kg), high free cover over the target is achieved and is associated with complete suppression of pKIT and downstream markers out to 8 hours. As the compound is cleared and cover declines, these signals recover although recovery is not complete even at 24 hours. |
Molecular Weight | 479.51 |
Formula | C24H26FN7O3 |
CAS No. | 2248003-60-1 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
H2O: Insoluble
DMSO: 95 mg/mL (198.12 mM)
You can also refer to dose conversion for different animals. More
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AZD3229 2248003-60-1 Tyrosine Kinase/Adaptors c-Kit Inhibitor AZD-3229 CD117 AZD 3229 SCFR inhibit inhibitor