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AVE-9488

Catalog No. T30219 CAS 291756-32-6

Synonyms: AVE 9488, AVE9488

AVE-9488 is a novel endothelial NO synthase (eNOS) enhancer that upregulates eNOS expression, induces NO production, and may ameliorate portal hypertension.

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AVE-9488, CAS 291756-32-6

Pack Size	Availability	Price/USD
1 mg	In stock	$ 293.00
5 mg	In stock	$ 722.00
10 mg	In stock	$ 987.00
25 mg	In stock	$ 1,520.00
50 mg	In stock	$ 1,980.00
100 mg	In stock	$ 2,500.00

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Purity: 99.87%

Biological Description

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Description

AVE-9488 is a novel endothelial NO synthase (eNOS) enhancer that upregulates eNOS expression, induces NO production, and may ameliorate portal hypertension.

Synonyms	AVE 9488, AVE9488
Molecular Weight	255.29
Formula	C16H14FNO
CAS No.	291756-32-6

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

References and Literature

1. Frantz S,et al. The eNOS enhancer AVE 9488: a novel cardioprotectant against ischemia reperfusion injury. Basic Res Cardiol. 2009 Nov;104(6):773-9. 2. Biecker E, et al. Treatment of bile duct-ligated rats with the nitric oxide synthase transcription enhancer AVE 9488 ameliorates portal hypertension. Liver Int. 2008 Mar;28(3):331-8. 3. Förstermann U, et al. Therapeutic effect of enhancing endothelial nitric oxide synthase (eNOS) expression and preventing eNOS uncoupling. Br J Pharmacol. 2011 Sep;164(2):213-23. 4. Schäfer A, et al. Inhibition of platelet activation in rats with severe congestive heart failure by a novel endothelial nitric oxide synthase transcription enhancer. Eur J Heart Fail. 2009 Apr;11(4):336-41.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

AVE-9488 291756-32-6 Immunology/Inflammation NO Synthase NOS AVE 9488 AVE9488 inhibitor inhibit

Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.