Powder: -20°C for 3 years
In solvent: -80°C for 2 years
AR-C155858 is an inhibitor of monocarboxylate transporter MCT1 and MCT2 (Kis: 2.3 nM and 10 nM).
Description | AR-C155858 is an inhibitor of monocarboxylate transporter MCT1 and MCT2 (Kis: 2.3 nM and 10 nM). |
Targets&IC50 | MCT2:10 nM(ki), MCT1:(ki)2.3 nM |
In vitro | AR-C155858 (10 nM-100 nM) inhibits MCT1/MCT2 C-terminal chimaeras[1]. AR-C155858 inhibits MCT1 expressed in Xenopus oocytes in a time- and concentration-dependent manner[2]. AR-C155858 inhibits MCT2, and the 70% inhibition seen at 10 nM is followed by a gradually increasing inhibition which can only be explained by a Ki value of significantly less than 10 nM. |
Molecular Weight | 461.54 |
Formula | C21H27N5O5S |
CAS No. | 496791-37-8 |
Powder: -20°C for 3 years
In solvent: -80°C for 2 years
DMSO: 40 mg/mL (86.67 mM)
( < 1 mg/ml refers to the product slightly soluble or insoluble )
You can also refer to dose conversion for different animals. More
bottom
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
AR-C155858 496791-37-8 离子通道 Monocarboxylate transporter inhibit Inhibitor Monocarboxylate Transporter AR-C-155858 ARC155858 AR C155858 inhibitor