Powder: -20°C for 3 years | In solvent: -80°C for 1 year
AR-C155858 is an inhibitor of monocarboxylate transporter MCT1 and MCT2 (Kis: 2.3 nM and 10 nM).
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 97.00 | |
5 mg | In stock | $ 297.00 | |
10 mg | In stock | $ 517.00 | |
25 mg | In stock | $ 843.00 | |
50 mg | In stock | $ 1,160.00 | |
100 mg | In stock | $ 1,570.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 312.00 |
Description | AR-C155858 is an inhibitor of monocarboxylate transporter MCT1 and MCT2 (Kis: 2.3 nM and 10 nM). |
Targets&IC50 | MCT2:10 nM(ki), MCT1:(ki)2.3 nM |
In vitro | AR-C155858, at concentrations ranging from 10 nM to 100 nM, effectively inhibits the activity of MCT1/MCT2 C-terminal chimeras[1]. This compound also demonstrates time- and concentration-dependent inhibition of MCT1 when expressed in Xenopus oocytes[2]. Furthermore, AR-C155858 exhibits an inhibitory effect on MCT2, achieving 70% inhibition at 10 nM, with inhibition levels increasing gradually, indicative of a dissociation constant (Ki) value significantly lower than 10 nM. |
Molecular Weight | 461.53 |
Formula | C21H27N5O5S |
CAS No. | 496791-37-8 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 40 mg/mL (86.67 mM)
You can also refer to dose conversion for different animals. More
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AR-C155858 496791-37-8 Membrane transporter/Ion channel Monocarboxylate transporter inhibit Inhibitor AR-C-155858 AR-C 155858 Monocarboxylate Transporter ARC155858 AR C155858 inhibitor