Powder: -20°C for 3 years | In solvent: -80°C for 1 year
7,4'-Dihydroxyflavone (4',7-Dihydroxyflavone) can induce transcription of nodulation (nod) genes in Rhizobium meliloti. It has inhibitory activities against COX-2.
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5 mg | In stock | $ 50.00 | |
10 mg | In stock | $ 83.00 | |
25 mg | In stock | Inquiry | |
50 mg | In stock | Inquiry | |
1 mL * 10 mM (in DMSO) | In stock | $ 55.00 |
Description | 7,4'-Dihydroxyflavone (4',7-Dihydroxyflavone) can induce transcription of nodulation (nod) genes in Rhizobium meliloti. It has inhibitory activities against COX-2. |
Targets&IC50 | NCI-H292 cells:1.4 μM (NCI-H292 human airway epithelial cell) (IC50) |
In vitro | Root exudate from 3-day-old alfalfa seedlings was purified and then assayed for biological activity with a nodABC-lacZ fusion in R. meliloti. Indentities of major nod inducers were established by spectroscopic analyses (ultraviolet/visible, proton nuclear magnetic resonance, and mass spectroscopy) and comparison with authentic standards. Major nod inducers, which were identified as 4',7-Dihydroxyflavone, 4'-7-dihydroxyflavanone, and 4,4'-dihydroxy-2'-methoxychalcone, were released from seedling roots at 54, 22, and 20 picomole.plant(-1).day(-1), respectively. Luteolin was not found in these root exudates. |
Source |
Synonyms | 4',7-Dihydroxyflavone |
Molecular Weight | 254.24 |
Formula | C15H10O4 |
CAS No. | 2196-14-7 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 250 mg/mL (983.32 mM)
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7,4'-Dihydroxyflavone 2196-14-7 Chromatin/Epigenetic DNA Damage/DNA Repair Immunology/Inflammation Microbiology/Virology Neuroscience NF-Κb COX NF-κB CCR HDAC NOD Inhibitor 7,4'Dihydroxyflavone inhibit Nuclear factor-κB 4',7-Dihydroxyflavone Nuclear factor-kappaB 7,4' Dihydroxyflavone CC chemokine receptor inhibitor