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5,7,8-Trimethoxyflavone

🥰Excellent
Catalog No. TN1995Cas No. 23050-38-6
Alias Norwogonin 5,7,8-trimethyl ether

5,7,8-Trimethoxyflavone (Norwogonin 5,7,8-trimethyl ether) is a compound extracted from *Andrographis paniculata*, exhibiting anti-inflammatory activity and NO inhibition.

5,7,8-Trimethoxyflavone

5,7,8-Trimethoxyflavone

🥰Excellent
Purity: 99.89%
Catalog No. TN1995Alias Norwogonin 5,7,8-trimethyl etherCas No. 23050-38-6
5,7,8-Trimethoxyflavone (Norwogonin 5,7,8-trimethyl ether) is a compound extracted from *Andrographis paniculata*, exhibiting anti-inflammatory activity and NO inhibition.
Pack SizePriceAvailabilityQuantity
1 mg$34In Stock
5 mg$76In Stock
10 mg$110In Stock
25 mg$210In Stock
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Purity:99.89%
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Product Introduction

Bioactivity
Description
5,7,8-Trimethoxyflavone (Norwogonin 5,7,8-trimethyl ether) is a compound extracted from *Andrographis paniculata*, exhibiting anti-inflammatory activity and NO inhibition.
In vitro
In RAW 264.7 macrophages, 5,7,8-Trimethoxyflavone (Norwogonin 5,7,8-trimethyl ether) decreases NO production in a dose-dependent manner at concentrations of 8, 16, 32, and 64 μM after 24 hours of treatment. The compound does not alter lipopolysaccharide (LPS)-induced (100 ng/mL) cell viability [1].
SynonymsNorwogonin 5,7,8-trimethyl ether
Chemical Properties
Molecular Weight312.32
FormulaC18H16O5
Cas No.23050-38-6
SmilesO=C1C=C(OC=2C(OC)=C(OC)C=C(OC)C12)C=3C=CC=CC3
Relative Density.1.242 g/cm3 (Predicted)
ColorYellow
AppearanceSolid
Storage & Solubility Information
Storagestore at low temperature,keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

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TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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Keywords

NOSynthaseNO SynthaseNO5,7,8-Trimethoxyflavone5,7,8Trimethoxyflavone5,7,8 Trimethoxyflavone
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