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β-Anhydroicaritin

Catalog No. T6S2140 CAS 38226-86-7

Synonyms: Anhydroicaritin, Beta-Anhydroicaritin

1. β-Anhydroicaritin exhibits immunosuppressive effect on the mouse macrophages stimulated by LPS. 2. β-Anhydroicaritin phytosomes can inhibit enhanced bone turnover induced by ovariectomy, improve BMD the biomechanical properties of vertebrae, without any stimulation on uterus. 3. β-Anhydroicaritin possesses significant protective effects on the zymosan-induced peritonitis mice, which might be associated with the regulation of Ca(2+); influx in macrophages and iNOS expression.

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β-Anhydroicaritin, CAS 38226-86-7

Pack Size	Availability	Price/USD
5 mg	In stock	$ 47.00
10 mg	In stock	$ 80.00
25 mg	In stock	$ 153.00
50 mg	In stock	$ 228.00
100 mg	In stock	$ 353.00
1 mL * 10 mM (in DMSO)	In stock	$ 52.00

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Purity: 96.95%

Biological Description

Chemical Properties

Storage & Solubility Information

Description

Source

Natural Products > Berberidaceae > Epimedium

Synonyms	Anhydroicaritin, Beta-Anhydroicaritin
Molecular Weight	368.38
Formula	C21H20O6
CAS No.	38226-86-7

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 3.68 mg/mL (10 mM)

References and Literature

1. Gao Y, Xu G, Ma L, et al. Icarisid I specifically facilitates ATP or nigericin-induced NLRP3 inflammasome activation and causes idiosyncratic hepatotoxicity[J]. Cell Communication and Signaling. 2020 2. Wang Z, Xu G, Wang H, et al. Icariside Ⅱ Contributes to Epimedii folium-Induced Hepatotoxicity Through Enhancing NLRP3 Inflammasome Activation[J]. Epimedii folium. 2019. 3. Gao Y, Xu G, Ma L, et al. Icarisid I specifically facilitates ATP or nigericin-induced NLRP3 inflammasome activation and causes idiosyncratic hepatotoxicity[J]. Cell Communication and Signaling. 2020 4. Gao Y, Xu G, Ma L, et al. Icariside I specifically facilitates ATP or nigericin-induced NLRP3 inflammasome activation and causes idiosyncratic hepatotoxicity[J]. Cell Communication and Signaling. 2021, 19(1): 1-14.

Citations

1. Wang Z, Xu G, Wang H, et al. Icariside Ⅱ, a main compound in Epimedii Folium, induces idiosyncratic hepatotoxicity by enhancing NLRP3 inflammasome activation. Acta Pharmaceutica Sinica B. 2020 2. Gao Y, Xu G, Ma L, et al. Icariside I specifically facilitates ATP or nigericin-induced NLRP3 inflammasome activation and causes idiosyncratic hepatotoxicity. Cell Communication and Signaling. 2021 Feb 11;19(1):13. doi: 10.1186/s12964-020-00647-1. 3. Gao Y, Xu G, Ma L, et al. Icarisid I specifically facilitates ATP or nigericin-induced NLRP3 inflammasome activation and causes idiosyncratic hepatotoxicity. Cell Communication and Signaling. 2020

Related compound libraries

This product is contained In the following compound libraries：

Miao medicine Compound Library Anti-Cancer Active Compound Library Inhibitor Library Traditional Chinese Medicine Monomer Library Protease Inhibitor Library RO5 Drug-like Natural Product Library Anti-Cancer Compound Library Immunology/Inflammation Compound Library Anti-Fibrosis Compound Library Apoptosis Compound Library

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

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Keywords

β-Anhydroicaritin 38226-86-7 Apoptosis Immunology/Inflammation Others Proteases/Proteasome TNF MMP Interleukin βAnhydroicaritin TNFR β Anhydroicaritin Anhydroicaritin Beta-Anhydroicaritin Interleukin Related Matrix metalloproteinases inhibit Inhibitor TNF Receptor Tumor Necrosis Factor Receptor b-Anhydroicaritin inhibitor

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