TRP/TRPV Channel

TRPV is a family of transient receptor potential cation channels (TRP channels) in animals. All TRPVs are highly calcium selective. TRP channels are a large group of ion channels consisting of six protein families, located mostly on the plasma membrane of numerous human and animal cell types, and in some fungi.

Cat. No.	Product name	CAS No.	Purity
T2539	Fingolimod hydrochloride	162359-56-0	99.69%
T2539	Fingolimod hydrochloride (FTY720) , a novel immune modulator, is a sphingosine 1-phosphate (S1P) antagonist (IC50: 0.033 nM in K562 and NK cells).
T4680L	HC067047 Hydrochloride(883031-03-6 free base)	1481646-76-7	99.68%
T4680L	HC-067047 hydrochloride is a potent and selective TRPV4 antagonist. HC-067047 hydrochloride reversibly inhibited currents through the human, rat, and mouse TRPV4...
T12514	Podocarpic acid	5947-49-9	99.67%
T12514	Podocarpic acid is a natural product and a novel TRPA1 activator.
T1109	(Z)-Capsaicin	25775-90-0	99.67%
T1109	(Z)-Capsaicin (Zucapsaicin) is a medication used to treat osteoarthritis of the knee and Others neuropathic pain.(Z)-Capsaicin is a synthetic cis isomer of natur...
T6379	AMG 517	659730-32-2	99.66%
T6379	AMG 517 is an effective and specific TRPV1 antagonist, antagonizes proton (IC50: 0.76 nM), capsaicin (IC50: 0.62 nM), and heat activation (IC50: 1.3 nM) of TRPV1...
T2163	Dihydrocapsaicin	19408-84-5	99.61%
T2163	Dihydrocapsaicin (CCRIS1589) is isolated from Capsicum fruit. Capsaicin is the primary active component of the heat and pain-eliciting lipid soluble fraction of ...
T9263	Cim0216	1031496-06-6	99.6%
T9263	CIM0216 is a synthetic TRPM3 activator whose potency and apparent affinity greatly exceeds that of the canonical TRPM3 agonist.
TN1377	α-Spinasterol	481-18-5	99.58%
TN1377	α-Spinasterol is a transient receptor potential vanilloid 1 (TRPV1) antagonist, has anti-inflammatory, antidepressant, antioxidant and antinociceptive effects. α...
T2952	Camphor	76-22-2	99.53%
T2952	Camphor (2-Camphanone) is a bicyclic monoterpene ketone found widely in plants, especially CINNAMOMUM CAMPHORA. It is used topically as a skin antipruritic and a...
T5786	TETRAHYDROPIPERINE	23434-88-0	99.51%
T5786	Tetrahydropiperine (Cosmoperine) is a natural product derived from piperine, can be used to treat convulsion, epilepsy, relieve pain, and control insects.
T19723	AMTB hydrochloride	926023-82-7	99.51%
T19723	AMTB hydrochloride (AMTB HCl) is a novel TRPM8 channel blocker and is effective for pain and urinary diseases. AMTB can act on the bladder afferent pathway to at...
T12307	OMDM-6	616884-67-4	99.49%
T12307	OMDM-6 is a dual agonist of TRPV1(EC50 = 75 nM) and CB1 (Ki = 3.2 μM). OMDM-6 inhibits anandamide cellular uptake with a Ki of 7.0 μM.
T8565	N4-benzyl-N2-methylquinazoline-2,4-diamine hydrochloride	1135272-09-1	99.48%
T8565	N4-benzyl-N2-methylquinazoline-2,4-diamine hydrochloride is an inhibitor of TRPC4.
T16687	Pyr3	1160514-60-2	99.47%
T16687	Pyr3 is a selective transient receptor potential canonical channel 3 inhibitor. Pyr3 inhibits TRPC3-mediated Ca2+ influx in a dose-dependent manner(IC50 = 700 nM...
T28118	MSP3	1820968-63-5	99.46%
T28118	MSP3 is an agonist of TRPV1 (EC50 = 0.87 μM) and shows antinociceptive and neuroprotective effects.
T29522L	(S)-ABT 102	808756-70-9	99.41%
T29522L	N-[(1S)-5-tert-butyl-2,3-dihydro-1H-inden-1-yl]-N'-1H-indazol-4-ylurea is a potent TRPV1 antagonist, blocking activation of TRPV1 by capsaicin with the IC50 of 1...
T10247	Adenosine 5'-diphosphoribose sodium	68414-18-6	99.38%
T10247	Adenosine 5'-diphosphoribose sodium (ADP ribose sodium) is a metabolite of nicotinamide adenine nucleotide (NAD+), which is widely present in organisms.Adenosine...
T5454	N-(p-amylcinnamoyl) Anthranilic Acid	110683-10-8	99.35%
T5454	N-(p-amylcinnamoyl) Anthranilic Acid (ACA) is a broad spectrum Phospholipase A2 (PLA2) inhibitor and TRP channel blocker.
T1622	Rosiglitazone maleate	155141-29-0	99.33%
T1622	Rosiglitazone maleate (BRL 49653) is the maleate salt of rosiglitazone, an orally-active thiazolidinedione with antidiabetic properties and potential antineoplas...
T11394	GFB-8438	2304549-73-1	99.29%
T11394	GFB-8438 is a potent and subtype selective inhibitor of TRPC5(IC50s of 0.18 and 0.29 μM of hTRPC5 and hTRPC4, respectively).