β-lactamase — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T35427	β-Lactamase-IN-2		Antibacterial
	β-Lactamase-IN-2 is an inhibitor of β-Lactamase with anti-microbial and anti-bacterial effects.		Antibacterial
T38476	Metallo β-lactamase ligand 1		Antibacterial
	Metallo β-lactamase ligand 1 is an inhibitor of class B β-lactamase exhibiting antibacterial activities.		Antibacterial
T19206	β-Lactamase-IN-1	4-(1,3-dihydroxypropan-2-yl)-6-methoxypyrido[2,3-b]pyrazin-3-one,beta-lactamase-IN-1	Antibacterial
	β-Lactamase-IN-1 (4-(1,3-dihydroxypropan-2-yl)-6-methoxypyrido[2,3-b]pyrazin-3-one) is a β-Lactamase inhibitor and targets the infection of Neisseria gonorrhoeae.		Antibacterial
T38956	β-Lactamase-IN-5
	β-Lactamase-IN-5, a β-lactamase inhibitor isolated from compound 720, holds significant potential for studying bacterial infections.
T38955	β-Lactamase-IN-4
	β-Lactamase-IN-4 (WO2013149121A1, compound 708) is a potent β-lactamase inhibitor. It serves as a valuable tool in the investigation of bacterial infections.
T39865	β-Lactamase-IN-6
	β-Lactamase-IN-6 is a β-Lactamase inhibitor that shows high antibacetrial activity.
T14979	Clavulanate lithium	Clavulanic acid lithium	Antibacterial
	Clavulanate lithium (Clavulanic acid lithium) is an inhibitor of β-lactamase.		Antibacterial
T60387	β-Lactamase-IN-8
	β-Lactamase-IN-8 (compound 20) is a potent and oral bioavailable broad-spectrum cyclic boronate β-lactamase inhibitor that can be used for researching antibacteria [1].
T60797	β-Lactamase-IN-7
	β-Lactamase-IN-7 (compound 14) effectively inhibit Klebsiella pneumoniae that is a potent inhibitor of VIM-Type metallo-β-lactamase with Ki values of 1.26 μM and 0.54 μM for VIM-1 and VIM-4, respectively [1].
T1550	Thiamphenicol	Dextrosulphenidol,Thiophenicol	Antibacterial , Antibiotic
	Thiamphenicol (Dextrosulphenidol) is a methylsulfonyl analog of chloramphenicol. It is an antibiotic and immunosuppressive agent.		Antibacterial , Antibiotic
T8620	Piperacillin	Pipril,Pipracil,Pipercillin	Antibacterial
	Piperacillin (Pipercillin) is a semisynthetic penicillin with wide spectrum of antimicrobial activity(particularly pseudomonas strains)		Antibacterial
T60282	Metallo-β-lactamase-IN-3
	Metallo-β-lactamase-IN-3 (compound 35) is a potent metallo-β-lactamases (MBL) inhibitor that has the potential to restore the activity of current β-lactam antibiotics and to offer an orthogonal strategy to the discovery ...
T60494	Metallo-β-lactamase-IN-7
	Metallo-β-lactamase-IN-7 is a potent inhibitor of VIM -Type metallo-β-lactamase with IC 50 s of 0.019 μM, 13.64 μM, 0.38 μM for VIM-2, VIM-1 and VIM-5, respectively. Metallo-β-lactamase-IN-7 also enhances the antibacter...
T60914	Metallo-β-lactamase-IN-8
	Metallo-β-lactamase-IN-8 (compound 17) is a potent, reversible and competitive broad-spectrum metallo-β-lactamases (MβLs) inhibitor with antibacterial activity. The IC50 values of Metallo-β-lactamase-IN-8 against L1, Imi...
T60370	Metallo-β-lactamase-IN-2
	Metallo-β-lactamase-IN-4 (compound 40) is a potent metallo-β-lactamases (MBL) inhibitor with IC 50 values of 0.1 μM for VIM-1, 1.3 μM for NDM-1 and 5.0 μM for IMP-7, respectively [1].
T79435	Metallo-β-lactamase-IN-11
	Metallo-β-lactamase-IN-11 (compound 5f), a potent inhibitor of Metallo-β-lactamases (MBLs), demonstrates efficacy against the bacterial metallophyllactamase CphA with an IC50 value of 45 µM. At a concentration of 10 µM, ...
T61173	Metallo-β-lactamase-IN-5
	Metallo-β-lactamase-IN-5 (compound 5c) is a powerful inhibitor of metallo-β-lactamases (MBLs). Its inhibitory activity against MBLs NDM-1 and VIM-1 has been demonstrated. With an IC50 value of 45 μg/mL, Metallo-β-lactama...
T60239	Metallo-β-lactamase-IN-6
	Metallo-β-lactamase-IN-6 is a highly effective inhibitor of VIM-Type metallo-β-lactamase, demonstrating IC 50 values of 0.56 μM, 29.50 μM, and 5.78 μM for VIM-2, VIM-1, and VIM-5, respectively. In addition, Metallo-β-lac...
T60694	Metallo-β-lactamase-IN-4
	Metallo-β-lactamase-IN-4 (compound 40) is a potent inhibitor of metallo-β-lactamases (MBL) with IC 50 values of 0.5 μM, 2.1 μM, and 3.3 μM for VIM-1, NDM-1 and IMP-7, respectively [1].
T72261	Metallo-β-lactamase-IN-9
	Metallo-β-lactamase-IN-9 (Compound 23) serves as a broad-spectrum inhibitor of metallo-beta-lactamases (MBL), exhibiting inhibition constants (IC50) of 35 nM for NDM-1, 269 nM for VIM-1, and 369 nM for IMP-1 [1].