20
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T19206 | β-Lactamase-IN-1 | 4-(1,3-dihydroxypropan-2-yl)-6-methoxypyrido[2,3-b]pyrazin-3-one,beta-lactamase-IN-1 | Antibacterial |
β-Lactamase-IN-1 (4-(1,3-dihydroxypropan-2-yl)-6-methoxypyrido[2,3-b]pyrazin-3-one) is a β-Lactamase inhibitor and targets the infection of Neisseria gonorrhoeae. | |||
T60454 | NDM-1 inhibitor-3 | Others | |
NDM-1 inhibitor-3 is a New Delhi Metallo-β-lactamase-1 (NDM-1) inhibitor (Ki : 4 μM) widely found in nature and is associated with antibiotic resistance. | |||
T60050 | ANT3310 | Antibacterial | |
ANT3310 is an inhibitor of broad-spectrum covalent Serine β-Lactamase with IC50s ranging from 1 nM to 175 nM for AmpC, CTX-M-15, TEM-1, OXA-48, OXA-23, and KPC-2. ANT3310 can be used in studies about bacterial infection. | |||
T16028 | IMB-XH1 | Mcl1-IN-2 | BCL , Antibacterial |
IMB-XH1 (Mcl1-IN-2) is a myeloid cell factor 1 (Mcl-1) inhibitor. | |||
T61173 | Metallo-β-lactamase-IN-5 | ||
Metallo-β-lactamase-IN-5 (compound 5c) is a powerful inhibitor of metallo-β-lactamases (MBLs). Its inhibitory activity against MBLs NDM-1 and VIM-1 has been demonstrated. With an IC50 value of 45 μg/mL, Metallo-β-lactama... | |||
T60387 | β-Lactamase-IN-8 | ||
β-Lactamase-IN-8 (compound 20) is a potent and oral bioavailable broad-spectrum cyclic boronate β-lactamase inhibitor that can be used for researching antibacteria [1]. | |||
T60282 | Metallo-β-lactamase-IN-3 | ||
Metallo-β-lactamase-IN-3 (compound 35) is a potent metallo-β-lactamases (MBL) inhibitor that has the potential to restore the activity of current β-lactam antibiotics and to offer an orthogonal strategy to the discovery ... | |||
T60239 | Metallo-β-lactamase-IN-6 | ||
Metallo-β-lactamase-IN-6 is a highly effective inhibitor of VIM-Type metallo-β-lactamase, demonstrating IC 50 values of 0.56 μM, 29.50 μM, and 5.78 μM for VIM-2, VIM-1, and VIM-5, respectively. In addition, Metallo-β-lac... | |||
T60494 | Metallo-β-lactamase-IN-7 | ||
Metallo-β-lactamase-IN-7 is a potent inhibitor of VIM -Type metallo-β-lactamase with IC 50 s of 0.019 μM, 13.64 μM, 0.38 μM for VIM-2, VIM-1 and VIM-5, respectively. Metallo-β-lactamase-IN-7 also enhances the antibacter... | |||
T60914 | Metallo-β-lactamase-IN-8 | ||
Metallo-β-lactamase-IN-8 (compound 17) is a potent, reversible and competitive broad-spectrum metallo-β-lactamases (MβLs) inhibitor with antibacterial activity. The IC50 values of Metallo-β-lactamase-IN-8 against L1, Imi... | |||
T60797 | β-Lactamase-IN-7 | ||
β-Lactamase-IN-7 (compound 14) effectively inhibit Klebsiella pneumoniae that is a potent inhibitor of VIM-Type metallo-β-lactamase with Ki values of 1.26 μM and 0.54 μM for VIM-1 and VIM-4, respectively [1]. | |||
T80721 | Zndm19 | ||
Zndm19 is an inhibitor of New Delhi Metallo-β-lactamase-1 (NDM-1), utilized in researching drug-resistant bacterial infections [1]. | |||
T69482 | MßL-IN-2I | ||
MßL-IN-2I is a potent broad-spectrum metallo-β-lactamase (MβL) inhibitor which inhibits the MβLs NDM-1, VIM-2, ImiS, and L1. | |||
T79317 | MBL-IN-1 | ||
MBL-IN-1 (compound 41), a β-Lactamase inhibitor, exhibits an IC50 range of 0.10 to 25.85 µM and is utilized in the study of bacterial infections [1]. | |||
T60694 | Metallo-β-lactamase-IN-4 | ||
Metallo-β-lactamase-IN-4 (compound 40) is a potent inhibitor of metallo-β-lactamases (MBL) with IC 50 values of 0.5 μM, 2.1 μM, and 3.3 μM for VIM-1, NDM-1 and IMP-7, respectively [1]. | |||
T60370 | Metallo-β-lactamase-IN-2 | ||
Metallo-β-lactamase-IN-4 (compound 40) is a potent metallo-β-lactamases (MBL) inhibitor with IC 50 values of 0.1 μM for VIM-1, 1.3 μM for NDM-1 and 5.0 μM for IMP-7, respectively [1]. | |||
T79435 | Metallo-β-lactamase-IN-11 | ||
Metallo-β-lactamase-IN-11 (compound 5f), a potent inhibitor of Metallo-β-lactamases (MBLs), demonstrates efficacy against the bacterial metallophyllactamase CphA with an IC50 value of 45 µM. At a concentration of 10 µM, ... | |||
T62486 | VIM-2-IN-1 | ||
VIM-2-IN-1 (compound 1dj) is a β-lactamase inhibitor with antibacterial activity. IC50: 48 μM) and New Delhi Metal (NDM-1) (IC50: 231 μM). | |||
T72261 | Metallo-β-lactamase-IN-9 | ||
Metallo-β-lactamase-IN-9 (Compound 23) serves as a broad-spectrum inhibitor of metallo-beta-lactamases (MBL), exhibiting inhibition constants (IC50) of 35 nM for NDM-1, 269 nM for VIM-1, and 369 nM for IMP-1 [1]. | |||
T38020 | O-Benzylhydroxylamine (hydrochloride) | ||
O-Benzylhydroxylamine is a building block.1,2It has been used in the synthesis of β-lactam inhibitor precursors and fluoroquinolone derivatives with antibiotic activity. 1.Bellettini, J.R., and Miller, M.J.A short synthe... |