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Search Results for " wnt3a "

Targets

3

Compounds

7

Recombinant Proteins

Cat No. Product Name Synonyms Targets
TP1263 Fz7-21 (Ac)-LPSDDLEFWCHVMY-NH2 Wnt/beta-catenin
Fz7-21 ((Ac)-LPSDDLEFWCHVMY-NH2) is a peptide antagonist of FZD7 . It antagonises WNT3A-induced Wnt-β-catenin signalling in HEK293 expressing FZD7. Fz7-21 impairs Wnt/β-catenin signaling in HEK293 cells stimulated with e...
T77780 Zamaporvint RXC004 Others
Zamaporvint (RXC004) is a selective, orally active and potent inhibitor of the Wnt pathway that acts on the membrane-bound fatty acyltransferase porcupine to block Wnt ligand palmitoylation, secretion, and pathway activa...
T36684 Ipivivint
Ipivivint, a first-in-class, orally active and potent CDC-like kinase (CLK) inhibitor, inhibits CLK1 (IC50=1.4 μM), CLK2 (IC50=0.002 μM) and CLK3 (IC50=0.022 μM). Ipivivint reduces Wnt pathway signaling gene expression t...

Recombinant Proteins

Cat No. Product Name Species Expression System
TMPY-06987 Wnt Surrogate/Wnt3a Protein, Recombinant Human HEK293 Cells
Wnt Surrogate/Wnt3a Protein, Recombinant is expressed in HEK293 mammalian cells with hFc tag.
TMPH-02859 Wnt3a Protein, Mouse, Recombinant (His) Mouse E. coli
Ligand for members of the frizzled family of seven transmembrane receptors. Functions in the canonical Wnt signaling pathway that results in activation of transcription factors of the TCF/LEF family. Required for normal ...
TMPH-01961 Wnt3a Protein, Human, Recombinant (His) Human E. coli
Ligand for members of the frizzled family of seven transmembrane receptors. Functions in the canonical Wnt signaling pathway that results in activation of transcription factors of the TCF/LEF family. Required for normal ...
TMPY-02115 R-Spondin 3/RSPO3 Protein, Human, Recombinant (aa 1-146, His) Human HEK293 Cells
R-spondin 3 (RSPO3) is a member of the R-Spondin (RSPO) family in vertebrates that activate Wnt/beta-catenin signaling, plays a key role in these processes. The RSPO family of secreted Wnt modulators is involved in devel...
TMPH-03392 5T4/TPBG Protein, Rat, Recombinant (His & SUMO) Rat E. coli
May function as an inhibitor of Wnt/beta-catenin signaling by indirectly interacting with LRP6 and blocking Wnt3a-dependent LRP6 internalization. 5T4/TPBG Protein, Rat, Recombinant (His & SUMO) is expressed in E. coli ex...
TMPH-02436 5T4/TPBG Protein, Cynomolgus, Recombinant (E. coli, His & Myc) Cynomolgus E. coli
May function as an inhibitor of Wnt/beta-catenin signaling by indirectly interacting with LRP6 and blocking Wnt3a-dependent LRP6 internalization. 5T4/TPBG Protein, Cynomolgus, Recombinant (E. coli, His & Myc) is expresse...
TMPH-02437 5T4/TPBG Protein, Cynomolgus, Recombinant (His & Myc) Cynomolgus HEK293 Cells
May function as an inhibitor of Wnt/beta-catenin signaling by indirectly interacting with LRP6 and blocking Wnt3a-dependent LRP6 internalization. 5T4/TPBG Protein, Cynomolgus, Recombinant (His & Myc) is expressed in HEK2...
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