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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
TP2207 | Pasireotide Acetate | Somatostatin | |
Pasireotide Acetate is a stable cyclohexapeptide somatostatin mimic | |||
TP1570L | Cortistatin-14 acetate | Cortistatin-14 acetate(186901-48-4 Free base) | Somatostatin |
Cortistatin-14 acetate, a neuropeptide have structural similarity to somatostatin-14, binds and exerts its function via the somatostatin receptors (sst1-sst5). Cortistatin-14 acetate shows anticonvulsive, neuroprotective... | |||
TP1346 | CYN 154806 TFA | CYN 154806 TFA | Somatostatin |
CYN 154806 TFA is a cyclic octapeptide and an effective selective somatostatin sst2 receptor antagonist. For the recombinant sst2, sst1, sst3, sst4 and sst5 receptors, the pIC50 values are 8.58, 5.41, 6.07, 5.76 and 6.48... | |||
TP1570 | Cortistatin-14 | ||
Cortistatin 14 is a neuropeptide expressed in inhibitory neurons of the cerebral cortex. Depresses neuronal activity, and induces slow-wave sleep, likely through antagonism of acetylcholine. It is structurally and functi... | |||
T23479 | TT 232 | Others | |
sst1/sst4 somatostatin receptors agonist | |||
T12368 | Pasireotide L-aspartate salt | SOM230 L-aspartate | Others |
Pasireotide L-aspartate salt is a stable cyclohexapeptide somatostatin mimic that exhibits unique high-affinity binding to human somatostatin receptors (subtypes sst1/2/3/4/5, pKi=8.2/9.0/9.1/<7.0/9.9 respectively). | |||
TP2045 | CH 275 | ||
Potent somatostatin receptor 1 (sst1) agonist; displays selectivity for sst1 (IC50 values are 30.9 nM, 345 nM, > 1 μM, > 10 μM and > 10μM for human sst1, sst3, sst4, sst2 and sst5 respectively). Attenuates somatostatin r... | |||
T76034 | Cortistatin-14 TFA | ||
Cortistatin-14 (TFA), a neuropeptide resembling somatostatin-14 in structure, operates through interaction with somatostatin receptors (sst1-sst5). This compound exhibits anticonvulsive and neuroprotective effects alongs... | |||
TP1877 | CYN 154806 | ||
CYN 154806 is a potent and selective somatostatin sst2 receptor antagonist, The pIC50 values are 8.58, 5.41, 6.07, 5.76 and 6.48 for human recombinant sst2, sst1, sst3, sst4 and sst5 receptors respectively. | |||
T12370 | Pasireotide | SOM 230,SOM 320 | Others |
Pasireotide(SOM 230) is a stable cyclohexapeptide somatostatin mimic that exhibits unique high-affinity binding to human somatostatin receptors (subtypes sst1/2/3/4/5, pKi=8.2/9.0/9.1/<7.0/9.9 respectively). | |||
T32511L | L-796,778 acetate | L-796,778 acetate(217480-25-6 Free base) | Somatostatin |
L-796,778 acetate is a slective somatostatin receptor agonist with IC50 of 24nM for sst3, for sst1, sst2, sst4 and sst5, IC50 is >1000nM. | |||
TP2122 | Seglitide | ||
Peptide agonist for sst2 and sst5 somatostatin receptors. IC50/Kd values (nM) at cloned human somatostatin receptors are: > 1000 (sst1), 0.2 - 1.5 (sst2), 27 - 36 (sst3), > 127 (sst4), and 0.06 - 23 (sst5). | |||
T75248 | Pasireotide (diaspartate) | ||
Pasireotide diaspartate (SOM230), a long-acting cyclohexapeptide and somatostatin analog, enhances agonist activity across somatostatin receptor subtypes (sst1/2/3/4/5, with pK i values of 8.2, 9.0, 9.1, <7.0, and 9.9, r... | |||
T28851 | SRA880 free base | SRA 880,NVPSRA880,NVP SRA880,NVP-SRA880,SRA-880,SRA880 | |
SRA880 is a non-peptide antagonist of somatostatin sst1-receptor. SRA880 displayed significantly lower affinity for the other human recombinant somatostatin receptors ( pK(d) < or = 6.0). SRA880 shows a certain binding a... | |||
T35663 | Cortistatin-29 (rat) (trifluoroacetate salt) | ||
Cortistatin-29 is a neuropeptide that is structurally similar to somatostatin-28. It is produced by cleavage of preprocortistatin to procortistatin, which is cleaved at dibasic amino acids to form cortistatin-29 and cort... | |||
T11800 | L-803087 | Somatostatin | |
L-803087 is a potent and selective agonist of the growth inhibitor sst4 receptor with a Ki value of 0.7 nM for sst4, which is more than 280-fold more selective than other growth inhibitory receptors.L-803087 induced AMPA... | |||
T76596 | PRL 3195 | ||
PRL 3195 is a somatostatin receptor antagonist, exhibiting K i values of 6, 17, 66, 1000, and 1000 nM for human somatostatin receptors sst 5 , sst 2 , sst 3 , sst 1 , and sst 4, respectively [1]. | |||
T13811 | Pasireotide ditrifluoroacetate | SOM230 ditrifluoroacetate,Pasireotide ditrifluoroacetate (396091-73-9 free base),Pasireotide TFA salt | Others |
Pasireotide is a stable cyclohexapeptide somatostatin mimic. | |||
T12369 | Pasireotide pamoate | SOM230 pamoate | Others |
Pasireotide pamoate is a stable cyclohexapeptide somatostatin mimic. Pasireotide pamoate exhibits antisecretory, antiproliferative, and proapoptotic activity. | |||
T39207 | L-803087 TFA | ||
L-803087 TFA is a highly potent and selective agonist of the somatostatin sst4 receptor, exhibiting a Ki value of 0.7 nM. It displays a remarkable selectivity, being over 280-fold more preferential for the sst4 receptor ... |