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Search Results for " sortilin "

7

Compounds

Cat No. Product Name Synonyms Targets
T72410 Sortilin antagonist 1
Sortilin Antagonist 1, a potent sortilin antagonist, exhibits an inhibition constant (IC50) of 20 nM against Neurotensin (NTS) binding to sortilin. Neurotensin acts as a sortilin ligand. This compound is utilized in neur...
T9044 SORT-PGRN interaction inhibitor 1 Neurotensin Receptor
SORT-PGRN interaction inhibitor 1 is a potent sortilin-progranulin interaction inhibitor(IC50 of 2 μM).
TQ0086 AF38469 AF-38469 Neurotensin Receptor
AF38469 is a new, specific and orally bioavailable Sortilin inhibitor (IC50: 330 nM).
T77053 Latozinemab GSK-4527223,AL-001 Neurotensin Receptor
Latozinemab (AL001) is a potent and selective recombinant humanized monoclonal antibody against Sortilin.Latozinemab has a high affinity for Sortilin and interrupts the interaction between the granule protein precursor (...
T13530 AF40431 Others
AF40431 is the first reported small-molecule ligand of sortilin (IC50: 4.4 µM; Kd: 0.7 µM). AF40431 is bound in the neurotensin-binding site of sortilin.
T70971 VGD020
VGD020 is a CD4 and sortilin inhibitor. It displayed activity for sortilin down-modulation and reduction of progranulin-induced breast cancer stem cell propagation.
T64206 VGD071
VGD071, a compound that targets sortilin, presents a promising avenue for forthcoming research utilizing mouse models of breast cancer.
TargetMol