Powder: -20°C for 3 years | In solvent: -80°C for 1 year
AF40431 is the first reported small-molecule ligand of sortilin (IC50: 4.4 μM; Kd: 0.7 μM). AF40431 is bound in the neurotensin-binding site of sortilin.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
2 mg | 5 days | $ 242.00 | |
5 mg | 5 days | $ 297.00 | |
25 mg | 6-8 weeks | $ 987.00 | |
50 mg | 6-8 weeks | $ 1,360.00 | |
100 mg | 6-8 weeks | $ 1,860.00 |
Description | AF40431 is the first reported small-molecule ligand of sortilin (IC50: 4.4 μM; Kd: 0.7 μM). AF40431 is bound in the neurotensin-binding site of sortilin. |
Targets&IC50 | Sortilin:4.4 µM (sortilin) Kd: 0.7 µM (IC50) |
Molecular Weight | 319.35 |
Formula | C17H21NO5 |
CAS No. | 181125-92-8 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 25 mg/mL (78.28 mM), when pH is adjusted to 1 with TFA. Sonication is recommended.
You can also refer to dose conversion for different animals. More
bottom
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
AF40431 181125-92-8 Others AF-40431 AF 40431 inhibitor inhibit